Our understanding of cancer genomes has allowed for the integration of molecular data into
histopathological classifications for routine stratification of patients. In the last 10–15 years …

This study aims to elucidate the clinical and molecular characteristics, treatment outcomes
and prognostic factors of patients with histone H3 K27-mutant diffuse midline glioma. We …

Simple Summary Midline gliomas are tumors that can manifest as either circumscribed or
diffuse growths. These tumors typically develop in midline structures, including the thalamus …

4| DISCUSSION This case represents a rare example of a diffusely infiltrating HGG centered
in the cerebral hemisphere harboring H3F3A p. K27M mutation [1] and the first to our …

To the Editor: The current World Health Organization (WHO) classification of tumors of the
CNS clarified the definition of the diffuse midline glioma (DMG), H3 K27-altered, in which …

Genetic histone variants have been implicated in cancer development and progression.
Mutations affecting the histone 3 (H3) family, H3. 1 (encoded by HIST1H3B and HIST1H3C) …

Background Histone mutant gliomas (HMG) with histone H3 K27 and G34 mutations are
recognized as biologically discrete entities with distinct anatomical locations, younger age at …

This work concerns the early evaluation of synthetic strategies towards the recently
discovered natural product camporidine A, which displays a pronounced anti-metastatic …