Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Breast cancer has become a leading cause of cancer-related deaths in women worldwide.
DNA methylation has been revealed to play an enormously important role in the …

Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …

Oxidative stress results from a persistent imbalance in oxidation levels that promotes
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …

Histone deacetylases (HDAC) and histone deacetylase inhibitors (HDACi) have greatly
impacted the war on cancer. Their role in epigenetics has significantly altered the …

Stilbenes are characterized by a vinyl group connecting two benzene rings to form the basic
parent nucleus. Hydrogen atoms on different positions of the benzene rings can be …

Herein, I present an updated and contextualized literature review of functional genomic
studies of natural phenols in the context of cancer. I suggest multilevel chemopreventive and …

The Mediterranean diet is recognized as a sustainable dietary approach with beneficial
health effects. This is highly relevant, although the production of typical Mediterranean food …

Breast cancer (BC) diagnosis has been associated with significant risk factors, including
family history, late menopause, obesity, poor eating habits, and alcoholism. Despite the …

The crosstalk between oncogenic signaling pathways plays a crucial role in driving cancer
development. We previously demonstrated that dietary polyphenols, specifically resveratrol …