Abstract Ethnopharmacological relevance Palmatine (Pal) is a major bioactive alkaloid
originated from ancient Chinese herbal medicine Cortex Phellodendri Amurensis (CPA) …

Gout that caused by hyperuricemia affects human health seriously and more efficient drugs
are urgently required clinically. In this study, a novel peptide named RDP1 (AAAAGAKAR …

Shogaol, an alkylphenol compound purified from the root and stem of ginger (Zingiber
officinale), has attracted considerable interest due to its potential anticancer, antioxidative …

Objectives To assess the cost-effectiveness of various combinations of urate lowering
therapy (ULT) and anti-inflammatory treatment in the management of newly diagnosed gout …

Hyperuricemia (HUA) is caused by increased synthesis and/or insufficient excretion of uric
acid (UA). Long-lasting HUA may lead to a number of diseases including gout and kidney …

Introduction/objectives Lesinurad, in combination with allopurinol, has been approved for
treatment of patients with gout which do not reach therapeutic serum urate target with …

Up to 90% of gout patients experience low uric acid (UA) excretion rather than high UA
production. The selective UA reabsorption inhibitor lesinurad (Zurampic®) is an effective …

Objectives. To assess the cost-effectiveness of various combinations of urate lowering
therapy (ULT) and anti-inflammatory treatment in the management of newly diagnosed gout …

Allopurinol/lesinurad appears to be cost effective for the management of gout or
hyperuricaemia in Italy, according to findings of a Grunenthal Italia-funded study published …