Could microRNAs contribute to the maintenance of β cell identity?
H Kaspi, R Pasvolsky, E Hornstein - Trends in Endocrinology & Metabolism, 2014 - cell.com
Normal physiology depends on defined functional output of differentiated cells. However,
differentiated cells are often surprisingly fragile. As an example, phenotypic collapse and …
differentiated cells are often surprisingly fragile. As an example, phenotypic collapse and …
Laser capture microdissection–reduced representation bisulfite sequencing (LCM-RRBS) maps changes in DNA methylation associated with gonadectomy-induced …
M Schillebeeckx, A Schrade, AK Löbs… - Nucleic acids …, 2013 - academic.oup.com
DNA methylation is a mechanism for long-term transcriptional regulation and is required for
normal cellular differentiation. Failure to properly establish or maintain DNA methylation …
normal cellular differentiation. Failure to properly establish or maintain DNA methylation …
Translational implications of the β-cell epigenome in diabetes mellitus
JS Johnson, C Evans-Molina - Translational Research, 2015 - Elsevier
Diabetes mellitus is a disorder of glucose homeostasis that affects more than 24 million
Americans and 382 million individuals worldwide. Dysregulated insulin secretion from the …
Americans and 382 million individuals worldwide. Dysregulated insulin secretion from the …
Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret
M Schillebeeckx, M Pihlajoki, E Gretzinger… - Molecular and cellular …, 2015 - Elsevier
Gonadectomy (GDX) induces sex steroid-producing adrenocortical tumors in certain mouse
strains and in the domestic ferret. Transcriptome analysis and DNA methylation mapping …
strains and in the domestic ferret. Transcriptome analysis and DNA methylation mapping …
A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines
NS Lee, JG Rohan, M Zitting, S Kamath, A Weitz… - Plos one, 2012 - journals.plos.org
Many research studies use immortalized cell lines as surrogates for primary beta-cells. We
describe the production and use of a novel “indirect" dual-fluorescent reporter system that …
describe the production and use of a novel “indirect" dual-fluorescent reporter system that …
[图书][B] Methods and Mechanisms of DNA methylation in Development and Disease
MA Schillebeeckx - 2014 - search.proquest.com
DNA methylation is a mechanism for long-term transcriptional regulation and is required for
normal cellular differentiation. Failure to properly establish or maintain DNA methylation …
normal cellular differentiation. Failure to properly establish or maintain DNA methylation …
[PDF][PDF] A Novel Dual-Color Reporter for Identifying Insulin-Producing Beta-Cells and Classifying
NS Lee, JG Rohan, M Zitting, S Kamath, A Weitz - 2012 - academia.edu
Many research studies use immortalized cell lines as surrogates for primary beta-cells. We
describe the production and use of a novel ''indirect''dual-fluorescent reporter system that …
describe the production and use of a novel ''indirect''dual-fluorescent reporter system that …
[引用][C] Translational implications of the b-cell epigenome in diabetes mellitus
JS JOHNSON, C EVANS-MOLINA - 2014