The bursa of Fabricius is critical for the normal development of B lymphocytes in birds. It is
productively colonized during embryonic life by a limited number of B cell precursors that …

Immunoglobulin IgY is the major antibody produced by chickens (Gallus domesticus). After
their VC gene is rearranged in B cells, IgY is continually synthesized, excreted into the blood …

We have analyzed immunoglobulin light chain sequences from avian leukosis virus (ALV)
induced bursal and metastatic tumors and from cell lines derived from these tumors …

The compartment of mouse B cell progenitors can be resolved Into five developmentally
related fractions by multicolor flow cytometry. Using this system and employing mutant mice …

Summary lleal Peyer's patches (IPPs) in the sheep are composed of tightly packed follicles
in which surface IgM-positive B cells proliferate and can be exported to the periphery. We …

Publisher Summary The chapter focuses on the actual knowledge of the formation of the B-
cell repertoire, including data on early B-cell commitment and the regulation of …

Small amount of antigen (1 µg) can be used to elicit an immune response in chickens and
there are low intra-individual differences regarding antibody concentration found in yolk. By …

Chicken immunoglobulin variable region diversity is generated during B-cell development in
the bursa of Fabricius by intrachromosomal gene conversion, resulting in the replacement of …

Sixteen D elements were characterized from the chicken genome, 15 of which are extremely
homologous. Early expression of this D repertoire was studied for both DJ and VDJ alleles …

The bursa of Fabricius is critical to normal B‐lymphocyte development in birds. During
embryonic life, B‐cell precursors migrate to the bursal rudiment and those which have …