Plant molecular farming: A viable platform for recombinant biopharmaceutical production
B Shanmugaraj, CJ I. Bulaon, W Phoolcharoen - Plants, 2020 - mdpi.com
The demand for recombinant proteins in terms of quality, quantity, and diversity is increasing
steadily, which is attracting global attention for the development of new recombinant protein …
steadily, which is attracting global attention for the development of new recombinant protein …
Chloroplast genomes: diversity, evolution, and applications in genetic engineering
Chloroplasts play a crucial role in sustaining life on earth. The availability of over 800
sequenced chloroplast genomes from a variety of land plants has enhanced our …
sequenced chloroplast genomes from a variety of land plants has enhanced our …
Green giant—a tiny chloroplast genome with mighty power to produce high‐value proteins: history and phylogeny
Free‐living cyanobacteria were entrapped by eukaryotic cells~ 2 billion years ago, ultimately
giving rise to chloroplasts. After a century of debate, the presence of chloroplast DNA was …
giving rise to chloroplasts. After a century of debate, the presence of chloroplast DNA was …
The potential for microalgae as bioreactors to produce pharmaceuticals
N Yan, C Fan, Y Chen, Z Hu - International journal of molecular sciences, 2016 - mdpi.com
As photosynthetic organisms, microalgae can efficiently convert solar energy into biomass.
Microalgae are currently used as an important source of valuable natural biologically active …
Microalgae are currently used as an important source of valuable natural biologically active …
Plant glycosides and glycosidases: a treasure-trove for therapeutics
K Kytidou, M Artola, HS Overkleeft… - Frontiers in plant …, 2020 - frontiersin.org
Plants contain numerous glycoconjugates that are metabolized by specific
glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing …
glucosyltransferases and hydrolyzed by specific glycosidases, some also catalyzing …
[HTML][HTML] The potential of plants as a system for the development and production of human biologics
The growing promise of plant-made biologics is highlighted by the success story of ZMapp™
as a potentially life-saving drug during the Ebola outbreak of 2014-2016. Current plant …
as a potentially life-saving drug during the Ebola outbreak of 2014-2016. Current plant …
Role of orally induced regulatory T cells in immunotherapy and tolerance
Oral antigen administration to induce regulatory T cells (Treg) takes advantage of regulatory
mechanisms that the gastrointestinal tract utilizes to promote unresponsiveness against food …
mechanisms that the gastrointestinal tract utilizes to promote unresponsiveness against food …
Recent achievements obtained by chloroplast transformation
Chloroplasts play a great role for sustained wellbeing of life on the planet. They have the
power and raw materials that can be used as sophisticated biological factories. They are rich …
power and raw materials that can be used as sophisticated biological factories. They are rich …
[HTML][HTML] Oral delivery of novel human IGF-1 bioencapsulated in lettuce cells promotes musculoskeletal cell proliferation, differentiation and diabetic fracture healing
Human insulin-like growth factor-1 (IGF-1) plays important roles in development and
regeneration of skeletal muscles and bones but requires daily injections or surgical …
regeneration of skeletal muscles and bones but requires daily injections or surgical …
Oral delivery of protein drugs bioencapsulated in plant cells
Plants cells are now approved by the FDA for cost-effective production of protein drugs
(PDs) in large-scale current Good Manufacturing Practice (cGMP) hydroponic growth …
(PDs) in large-scale current Good Manufacturing Practice (cGMP) hydroponic growth …