The rise of regulatory RNA

KV Morris, JS Mattick - Nature Reviews Genetics, 2014 - nature.com
Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

The significant other: splicing by the minor spliceosome

JJ Turunen, EH Niemelä, B Verma… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
The removal of non‐coding sequences, introns, from the mRNA precursors is an essential
step in eukaryotic gene expression. U12‐type introns are a minor subgroup of introns …

[HTML][HTML] Remote control of gene function by local translation

H Jung, CG Gkogkas, N Sonenberg, CE Holt - Cell, 2014 - cell.com
The subcellular position of a protein is a key determinant of its function. Mounting evidence
indicates that RNA localization, where specific mRNAs are transported subcellularly and …

Rates of in situ transcription and splicing in large human genes

J Singh, RA Padgett - Nature structural & molecular biology, 2009 - nature.com
Transcription and splicing must proceed over genomic distances of hundreds of kilobases in
many human genes. However, the rates and mechanisms of these processes are poorly …

Novel approach to enriching glycosylated RNAs: specific capture of glycoRNAs via solid-phase chemistry

J Li, S Yue, Z Gao, W Hu, Z Liu, G Xu, Z Wu… - Analytical …, 2023 - ACS Publications
Ribonuclease (RNA) modifications can alter cellular function and lead to differential immune
responses by acting as discriminators between RNAs from different phyla. RNA …

The life of U6 small nuclear RNA, from cradle to grave

AL Didychuk, SE Butcher, DA Brow - Rna, 2018 - rnajournal.cshlp.org
Removal of introns from precursor messenger RNA (pre-mRNA) and some noncoding
transcripts is an essential step in eukaryotic gene expression. In the nucleus, this process of …

Posttranscriptional gene silencing in nuclei

P Hoffer, S Ivashuta, O Pontes… - Proceedings of the …, 2011 - National Acad Sciences
In plants, small interfering RNAs (siRNAs) with sequence homology to transcribed regions of
genes can guide the sequence-specific degradation of corresponding mRNAs, leading to …

Effects of essential oil decanal on growth and transcriptome of the postharvest fungal pathogen Penicillium expansum

T Zhou, X Wang, B Ye, L Shi, X Bai, T Lai - Postharvest Biology and …, 2018 - Elsevier
Penicillium expansum is a destructive phytopathogen provoking the blue mold decay of
pome fruits and producing a polyketide-derived mycotoxin, patulin. In this study, the effects …

Cytoplasmic intron retention, function, splicing, and the sentinel RNA hypothesis

PT Buckley, M Khaladkar, J Kim… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
Cytoplasmic splicing represents a newly emerging level of transcriptional regulation adding
to the molecular diversity of mammalian cells. As examples of this noncanonical form of …

LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non-small cell lung cancer

B Zhu, M Finch-Edmondson, KW Leong, X Zhang… - Cell death …, 2021 - nature.com
Long non-coding RNAs (lncRNAs) regulate numerous biological processes involved in both
development and carcinogenesis. Hippo-YAP/TAZ signaling, a critical pathway responsible …