Aging-related hypoxia, oxidative stress, and inflammation pathophysiology are closely
associated with human age-related carcinogenesis and chronic diseases. However, the …

Background Cisplatin (DDP) is widely used to treat clinical malignant tumors, but it is also
accompanied by serious adverse reactions, such as brain nervous system injury. In clinical …

BACKGROUND: Randomised controlled trials have demonstrated prolonged survival with
new upfront treatments in addition to standard androgen deprivation therapy (ADT) in men …

Aging is a complex process marked by various changes at both cellular and systemic levels,
impacting the functioning and lifespan of organisms. Over time, researchers have pinpointed …

Whether neoadjuvant therapy confers a survival benefit in advanced prostate cancer (PCa)
remains uncertain. The primary endpoints of previous retrospective and phase II clinical …

It is imperative to identify patients with prostate cancer (PCa) who will benefit from androgen
receptor signaling inhibitors that can impact quality of life upon prolonged use. Using our …

Objectives To understand how best to further reduce the inappropriate use of pre‐surgical
androgen deprivation therapy (ADT), we investigated the determinants (influences) of ADT …

Prostate cancer (PCa) is most commonly observed in male patients. Although PCa
progresses relatively slowly, high-risk PCa is associated with an increased risk of lymph …

Prostate cancer (PCa) is most commonly observed in male patients. Although PCa
progresses relatively slowly, high-risk PCa is associated with an increased risk of lymph …

The Long and Winding Road from Guideline Recommendations to Improved Quality of Care. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …