Critical review of biodegradable and bioactive polymer composites for bone tissue engineering and drug delivery applications

S Sharma, P Sudhakara, J Singh, RA Ilyas… - Polymers, 2021 - mdpi.com
In the determination of the bioavailability of drugs administered orally, the drugs' solubility
and permeability play a crucial role. For absorption of drug molecules and production of a …

PLGA-based nanoparticles in cancer treatment

S Rezvantalab, NI Drude, MK Moraveji… - Frontiers in …, 2018 - frontiersin.org
Nanomedicines can be used for a variety of cancer therapies including tumor-targeted drug
delivery, hyperthermia, and photodynamic therapy. Poly (lactic-co-glycolic acid)(PLGA) …

Nanoencapsulation of food ingredients using carbohydrate based delivery systems

M Fathi, Á Martín, DJ McClements - Trends in food science & technology, 2014 - Elsevier
Highlights•Overview of carbohydrate based nano-delivery systems is provided.•Modification
methods to enhance carbohydrate functionality for target delivery are discussed.• …

Recent advances in the surface functionalization of PLGA-based nanomedicines

MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …

Polymeric nanoparticles—Tools in a drug delivery system in selected cancer therapies

M Madej, N Kurowska, B Strzalka-Mrozik - Applied Sciences, 2022 - mdpi.com
The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …

Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment

FA Khan, R Albalawi, FH Pottoo - Medicinal research reviews, 2022 - Wiley Online Library
Colon cancer is an adenocarcinoma, which subsequently develops into malignant tumors, if
not treated properly. The current colon cancer therapy mainly revolves around …

Insights into maleimide-thiol conjugation chemistry: Conditions for efficient surface functionalization of nanoparticles for receptor targeting

L Martínez-Jothar, S Doulkeridou, RM Schiffelers… - Journal of controlled …, 2018 - Elsevier
Maleimide-thiol chemistry is widely used for the design and preparation of ligand-decorated
drug delivery systems such as poly (lactide-co-glycolide)(PLGA) based nanoparticles (NPs) …

Drug delivery systems based on nanoparticles and related nanostructures

AVV Nikezić, AM Bondžić, VM Vasić - European Journal of Pharmaceutical …, 2020 - Elsevier
A new approach to drug design based on nanoparticles and related nanostructures for
effective drug delivery, is of great importance in future medical treatment, especially for …

Formulation and evaluation of pravastatin sodium-loaded PLGA nanoparticles: in vitro–in vivo studies assessment

SI Elsayed, GNS Girgis… - International Journal of …, 2023 - Taylor & Francis
Purpose Pravastatin sodium (PVS) is a hypolipidemic drug which suffers from extensive first-
pass metabolism and short half-life. Poly (d, l-lactide-co-glycolide)(PLGA) is considered a …

In vitro anti-leukemic assessment and sustained release behaviour of cytarabine loaded biodegradable polymer based nanoparticles

N Jan, A Madni, MA Rahim, NU Khan, T Jamshaid… - Life Sciences, 2021 - Elsevier
Aims The study aimed to develop, characterize, and evaluate poly (ɛ-caprolactone)(PCL)
based nanoparticles for the sustained release behaviour of cytarabine and to investigate the …