Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by
cognitive deficits and neuronal loss. Deposition of beta-amyloid peptide (Aβ) causes …

Numerous data reported in lampreys, which belong to the phylogenetically oldest branch of
vertebrates, show that the dopaminergic system was already well developed at the dawn of …

In natural systems, short-term food deprivation (dietary restriction, DR; calorie restriction,
CR) occurs frequently and animals have developed strategies to cope with this situation …

The vertebrate gene family for neuropeptide Y (NPY) receptors expanded by duplication of
the chromosome carrying the ancestral Y1–Y2–Y5 gene triplet. After loss of some …

Olanzapine-induced weight gain is associated with atherosclerosis, hypertension,
dyslipidemia, and diabetes. We synthesized a novel antipsychotic drug (PGW5) possessing …