Synthesis, molecular modeling, ADMET and fastness studies of some quinoline encompassing pyrimidine azo dye derivatives as potent antimicrobial agents

HD Trivedi, BY Patel, PK Patel, SR Sagar - Chemical Data Collections, 2022 - Elsevier
Targeting the current issue of microbial resistance and novel dye molecules for textile
industries, we have synthesized a series of novel Quinoline-Pyrimidine hybrids (3a–p). The …

Novel tetracycline hybrids: synthesis, characterization, docking studies and in-vitro evaluation of antibacterial activity

M Shah, B Suhagia, S Goswami, S Sagar… - Future Journal of …, 2025 - Springer
Background The biggest menace in the world today is the infection caused by pathogenic
bacteria in humans, where majority of the available antibiotics fail to provide therapeutic …

Fragment-based QSAR study to explore the structural requirements of DPP-4 inhibitors: a stepping stone towards better type 2 diabetes mellitus management

PK Dey, R Dutta, M Ray, P Jakkula… - SAR and QSAR in …, 2024 - Taylor & Francis
ABSTRACT Dipeptidyl peptidase-4 (DPP-4) inhibitors belong to a prominent group of
pharmaceutical agents that are used in the governance of type 2 diabetes mellitus (T2DM) …

Exploring Triazole Derivatives as DPP IV Inhibitors: Advancing Type II Diabetes Treatment via Molecular Structure Investigation and Pharmacophore Modelling

BM Shah, P Modi, P Trivedi - Chemistry Africa, 2024 - Springer
Purpose Diabetes is a serious global health concern attributable to high rate of morbidity
and mortality. Fortuitously, recent research has revealed the potential of glucagon-like …

Quinoline–Pyrimidine Monoazo Dye Hybrids: Synthesis, Catalyst Optimization, Molecular Docking and ADMET Studies, Biological Activity, and Dye Ability …

HD Trivedi, BY Patel, PK Patel, SR Sagar - Russian Journal of Organic …, 2023 - Springer
In order to develop motifs with the potential applications as drugs and dyes, a series of novel
quinoline–pyrimidine monoazo hybrids have been synthesized via the Biginelli reaction …

Design, Synthesis, Insilico and Invitro DPP‐4 Activity of Triazole based Heterocyclic Compounds

AK Tewari, RI Kumar, MI Nidhar - Chemistry & Biodiversity - Wiley Online Library
1, 2, 3‐triazole‐based ring connected with pyridazine, triazine, methyl pyrazole, diphenyl
pyrazole, and pthalimide moieties through propylene linker have been synthesized for …