[HTML][HTML] Pancreatic cancer: A review of epidemiology, trend, and risk factors

JX Hu, CF Zhao, WB Chen, QC Liu, QW Li… - World journal of …, 2021 - ncbi.nlm.nih.gov
Despite rapid advances in modern medical technology and significant improvements in
survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal …

Innate immunity and cancer pathophysiology

L Maiorino, J Daßler-Plenker, L Sun… - Annual Review of …, 2022 - annualreviews.org
Chronic inflammation increases the risk of several cancers, including gastric, colon, and
hepatic cancers. Conversely, tumors, similar to tissue injury, trigger an inflammatory …

Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC

JM Baer, C Zuo, LI Kang, AA de la Lastra… - Nature …, 2023 - nature.com
Tissue-resident macrophages (TRMs) are long-lived cells that maintain locally and can be
phenotypically distinct from monocyte-derived macrophages. Whether TRMs and monocyte …

Chronic pancreatitis is a risk factor for pancreatic cancer, and incidence increases with duration of disease: a systematic review and meta-analysis

S Gandhi, J De La Fuente, MH Murad… - Clinical and …, 2022 - journals.lww.com
METHODS: We searched electronic databases (MEDLINE, Embase, Web of Science,
Cochrane, and Scopus) and reference lists until January 18, 2021. Studies reporting …

Fatty change of the pancreas: the Pandora's box of pancreatology

MS Petrov - The Lancet Gastroenterology & Hepatology, 2023 - thelancet.com
Prevention of common diseases of the pancreas or interception of their progression is as
attractive in theory as it is elusive in practice. The fundamental challenge has been an …

Association of the microbiota and pancreatic cancer: opportunities and limitations

Z Chen, S Zhang, S Dong, H Xu, W Zhou - Frontiers in Immunology, 2022 - frontiersin.org
The human body is thoroughly colonized by a wide variety of microorganisms, termed
microbiota. Pancreatic cancer, one of the most aggressive forms of cancer, is no exception …

What is the evidence regarding the safety of new obesity pharmacotherapies

J Vidal, L Flores, A Jiménez, A Pané… - International Journal of …, 2024 - nature.com
The use of gut-hormone receptors agonists as new therapeutic options for obesity and some
of its related comorbidities, such as type 2 diabetes, has resulted in an unprecedented …

Post‐pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes

A Dugic, H Hagström, I Dahlman… - United European …, 2023 - Wiley Online Library
Background Post‐pancreatitis diabetes mellitus (PPDM) is a common consequence of
chronic pancreatitis (CP). We aimed to determine the incidence and predictors of PPDM …

[HTML][HTML] Independent validation and assay standardization of improved metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic …

UM Mahajan, B Oehrle, S Sirtl, A Alnatsha, E Goni… - Gastroenterology, 2022 - Elsevier
Background & Aims Pancreatic ductal adenocarcinoma cancer (PDAC) is a highly lethal
malignancy requiring efficient detection when the primary tumor is still resectable. We …

Modifiable and non-modifiable risk factors for the development of non-hereditary pancreatic cancer

M Olakowski, Ł Bułdak - Medicina, 2022 - mdpi.com
Pancreatic cancer is becoming an increasing healthcare concern. Though it is a 14th most
common cancer worldwide, its incidence is steadily rising. Results of currently available …