Asymmetric catalysis for the construction of quaternary carbon centres: nucleophilic addition on ketones and ketimines

O Riant, J Hannedouche - Organic & biomolecular chemistry, 2007 - pubs.rsc.org
There is a growing need in organic synthesis for efficient methodologies for the asymmetric
synthesis of quaternary carbon centres. One of the most attractive and straightforward …

Enantioselective catalytic formation of quaternary stereogenic centers

PG Cozzi, R Hilgraf… - European Journal of …, 2007 - Wiley Online Library
Enantioselective catalytic formation of tertiary stereogenic centers has nowadays reached
an impressive level of maturity, as is reflected in the large variety of available methods that …

Recent progress in the catalytic synthesis of tertiary alcohols from ketones with organometallic reagents

M Hatano, K Ishihara - Synthesis, 2008 - thieme-connect.com
Efficient tertiary alcohol synthesis is currently one of the most rapidly advancing fields in
organic chemistry, and recent powerful catalytic methodologies can provide versatile tertiary …

Highly diastereo-and enantioselective copper-catalyzed domino reduction/aldol reaction of ketones with methyl acrylate

J Deschamp, O Chuzel, J Hannedouche… - Angewandte Chemie …, 2006 - hal.science
A good choice: A new catalytic method was found for the construction of stereogenic
quaternary carbon centers through a copper-catalyzed domino conjugated reduction/aldol …

Asymmetric autocatalysis enables an improved synthesis of efavirenz

N Chinkov, A Warm, EM Carreira - Angewandte Chemie International …, 2011 - infona.pl
Asymmetric Autocatalysis Enables an Improved Synthesis of Efavirenz × Close The Infona
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Efficient Access to Multifunctional Trifluoromethyl Alcohols through Base‐Free Catalytic Asymmetric C− C Bond Formation with Terminal Ynamides

AM Cook, C Wolf - Angewandte Chemie International Edition, 2016 - Wiley Online Library
The asymmetric addition of terminal ynamides to trifluoromethyl ketones with a readily
available chiral zinc catalyst gives CF3‐substituted tertiary propargylic alcohols in up to 99 …

Bifunctional organo/metal cooperative catalysis with cinchona alkaloid scaffolds

L Stegbauer, F Sladojevich, DJ Dixon - Chemical Science, 2012 - pubs.rsc.org
Cooperative catalysis, inspired by the early findings on enzymatic activation, is a fast
growing research area. It refers to the combination of two or more catalytic species that …

Kinetic Resolution of Tertiary Propargylic Alcohols by Enantioselective Cu− H‐Catalyzed Si− O Coupling

J Seliger, X Dong, M Oestreich - … Chemie International Edition, 2019 - Wiley Online Library
A broad range of tertiary propargylic alcohols were kinetically resolved by catalyst‐
controlled enantioselective silylation. This non‐enzymatic kinetic resolution is catalyzed by a …

Recent progress in selective additions of organometal reagents to carbonyl compounds

M Hatano, T Miyamoto, K Ishihara - Current Organic Chemistry, 2007 - ingentaconnect.com
Carbon-carbon bond forming reactions are simple and direct methods for synthesizing the
various skeletons and the diverse structures of organic compounds. Even 100 years after the …

Enantioselective Alkynylation of Trifluoromethyl Ketones Catalyzed by Cation‐Binding Salen Nickel Complexes

D Park, CI Jette, J Kim, WO Jung, Y Lee… - Angewandte Chemie …, 2020 - Wiley Online Library
Cation‐binding salen nickel catalysts were developed for the enantioselective alkynylation
of trifluoromethyl ketones in high yield (up to 99%) and high enantioselectivity (up to 97 …