The enantioselective synthesis of spirocycles has long been pursued by organic chemists.
Despite their unique 3D properties and presence in several natural products, the difficulty in …

The cooperation and interplay between organic and metal catalyst systems is of utmost
importance in nature and chemical synthesis. Here innovative and selective cooperative …

Silica-supported metal complex catalysts have been developed and used for organic
transformations. The surface environment around the supported metal complex enhances …

Integrated catalysis is an emerging methodology that can streamline the multi-step synthesis
of complicated products in a single reaction vessel, achieving a high degree of control and …

The preparation of optically pure fine chemicals is among the most important and
challenging tasks met by organic chemists. Recently, significant efforts have been focused …

An efficient method for the synthesis of heterogeneous gold catalysts has been developed.
These catalysts were easily assembled from readily available silica materials and gold …

Confinement and cooperativity are important design principles used by Nature to optimize
catalytic activity in enzymes. In these biological systems, the precise sequence of the protein …

The immobilization of multiple functional groups on mesoporous silica has provided
opportunities to emulate the unique design principles and performances of enzymes. In this …

We describe a simple and general method for the preparation and molecular engineering of
supported trifunctional catalysts and their application in the representative Cu/TEMPO/NMI …

An asymmetric [3+ 2]-cycloaddition reaction of α, β-unsaturated 2-acyl imidazoles with
spirovinylcyclopropanyl-2-oxindoles catalyzed synergistically by an achiral palladium (0) …