Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline–Update 2022

ML Gauci, C Aristei, JC Becker, A Blom… - European Journal of …, 2022 - Elsevier
Merkel cell carcinoma (MCC) is a rare skin cancer, accounting for less than 1% of all
cutaneous malignancies. It is found predominantly in white populations and risk factors …

The biology and treatment of Merkel cell carcinoma: current understanding and research priorities

PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …

Merkel cell carcinoma: current US incidence and projected increases based on changing demographics

KG Paulson, SY Park, NA Vandeven… - Journal of the American …, 2018 - Elsevier
Background Merkel cell carcinoma (MCC) incidence rates are rising and strongly age-
associated, relevant for an aging population. Objective Determine MCC incidence in the …

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy

G Goh, T Walradt, V Markarov, A Blom, N Riaz… - …, 2015 - pmc.ncbi.nlm.nih.gov
Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous neuroendocrine
carcinoma, associated with the Merkel cell polyomavirus (MCPyV) in 80% of cases. To …

PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus, and overall survival

EJ Lipson, JG Vincent, M Loyo, LT Kagohara… - Cancer immunology …, 2013 - AACR
Merkel cell carcinoma (MCC) is a lethal, virus-associated cancer that lacks effective
therapies for advanced disease. Agents blocking the PD-1/PD-L1 pathway have shown …

[HTML][HTML] Diagnosis and treatment of Merkel Cell Carcinoma. European consensus-based interdisciplinary guideline

C Lebbe, JC Becker, JJ Grob, J Malvehy… - European journal of …, 2015 - Elsevier
Merkel cell carcinoma (MCC) is a rare tumour of the skin of neuro-endocrine origin probably
developing from neuronal mechanoreceptors. A collaborative group of multidisciplinary …

Merkel cell carcinoma: A review

NM Walsh, L Cerroni - Journal of Cutaneous Pathology, 2021 - Wiley Online Library
Merkel cell carcinoma has been a focus of active scientific investigation in recent years and
new information on the topic has emerged. Although uncommon, this primary cutaneous …

Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab

NA Giraldo, P Nguyen, EL Engle, GJ Kaunitz… - … for immunotherapy of …, 2018 - Springer
Background We recently reported a 56% objective response rate in patients with advanced
Merkel cell carcinoma (MCC) receiving pembrolizumab. However, a biomarker predicting …

Systematic literature review of efficacy, safety and tolerability outcomes of chemotherapy regimens in patients with metastatic Merkel cell carcinoma

P Nghiem, HL Kaufman, M Bharmal, L Mahnke… - Future …, 2017 - Taylor & Francis
Aim: Merkel cell carcinoma (MCC) is a rare neuroendocrine, cutaneous malignancy with
poor prognosis once metastasized. The aim of this study was to conduct a systematic …

[HTML][HTML] Systemic immune suppression predicts diminished merkel cell carcinoma–specific survival independent of stage

KG Paulson, JG Iyer, A Blom, EM Warton… - Journal of Investigative …, 2013 - Elsevier
Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy linked to a
contributory virus (Merkel cell polyomavirus). Multiple epidemiologic studies have …