Animal models of ocular tuberculosis: implications for diagnosis and treatment

S Basu, N Rao, P Elkington - Ocular Immunology and Inflammation, 2021 - Taylor & Francis
The pathogenesis of ocular tuberculosis (TB) has remained unclear due to the challenges of
performing mechanistic studies on clinical samples. Animal models have the potential to …

Role of regulatory T cells in tubercular uveitis

RK Sharma, A Gupta, S Kamal, R Bansal… - Ocular immunology …, 2018 - Taylor & Francis
Purpose: To study the role of regulatory T cells (Tregs) in patients with tubercular uveitis.
Methods: Frequencies of peripheral Tregs, Th1, Th17 cells, and intracellular cytokines were …

Transcriptional signatures of Mycobacterium tuberculosis in mouse model of intraocular tuberculosis

S Abhishek, MB Ryndak, A Choudhary… - Pathogens and …, 2019 - academic.oup.com
Background Studies on human intraocular tuberculosis (IOTB) are extremely challenging.
For understanding the pathogenesis of IOTB, it is important to investigate the mycobacterial …

Mycobacterium tuberculosis modulates fibroblast growth factor and vascular endothelial growth factor in ocular tuberculosis

N Singh, R Singh, RK Sharma, A Kumar… - Ocular Immunology …, 2021 - Taylor & Francis
Purpose: To evaluate the role of angiogenic growth factors in the pathogenesis of intraocular
tuberculosis. Methods: Retinal Pigment Epithelium (RPE) cells were infected with varying …

[PDF][PDF] Role of Regulatory T Cells in Tubercular Uveitis

MD Amod Gupta, R Bansal, MD Kusum Sharma… - 2016 - academia.edu
Purpose: To study the role of regulatory T cells (Tregs) in patients with tubercular uveitis.
Methods: Frequencies of peripheral Tregs, Th1, Th17 cells, and intracellular cytokines were …