Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

To maintain energy supply to the brain, a direct energy source called adenosine
triphosphate (ATP) is produced by oxidative phosphorylation and aerobic glycolysis of …

The effects of oxidative stress occur as a result of peroxidative damage of the
macromolecule and membranes of the cells and with the disruption of metabolic activities in …

Pesticides have been used in agriculture, public health programs, and pharmaceuticals for
many decades. Though pesticides primarily target pests by affecting their nervous system …

Maneb, a widely-used dithiocarbamate fungicide, remains in the environment and exerts
adverse health effects. Epidemiological evidence shows that maneb exposure is associated …

Abstract Parkinson's disease (PD), an age-related progressive neurodegenerative condition,
is associated with loss of dopaminergic neurons in the substantia nigra pars compacta …

Maneb is a typical dithiocarbamate fungicide that has been extensively used worldwide.
Epidemiological evidence shows that exposure to maneb is an environmental risk factor for …

Parkinson's disease (PD), a progressive neurodegenerative movement disorder, has
reached pandemic status worldwide. This neurologic disorder is caused primarily by the …

Parkinson's Disease (PD) is a progressive neurodegenerative disease characterized by loss
of dopaminergic neurons in substantia nigra pars compacta (SNpc). Iron (Fe)-dependent …

Maneb is a manganese-containing ethylene bisdithiocarbamate fungicide and is still
commonly used as no cases of resistance have been documented. However, studies have …