Modeling nontuberculous mycobacterial infections in zebrafish

MD Johansen, HP Spaink, SH Oehlers, L Kremer - Trends in Microbiology, 2024 - cell.com
The incidence of infections due to nontuberculous mycobacteria (NTM) has increased
rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent …

Recent advances in modelling Shigella infection

SL Miles, KE Holt, S Mostowy - Trends in Microbiology, 2024 - cell.com
Shigella is an important human-adapted pathogen which contributes to a large global
burden of diarrhoeal disease. Together with the increasing threat of antimicrobial resistance …

Use of zebrafish to identify host responses specific to type VI secretion system mediated interbacterial antagonism

M Virgo, S Mostowy, BT Ho - PLoS Pathogens, 2024 - journals.plos.org
Interbacterial competition is known to shape the microbial communities found in the host,
however the interplay between this competition and host defense are less clear. Here, we …

Zebrafish null mutants of Sept6 and Sept15 are viable but more susceptible to Shigella infection

V Torraca, MK Bielecka, MC Gomes, D Brokatzky… - …, 2023 - Wiley Online Library
Septins are evolutionarily conserved GTP‐binding proteins known for their roles in cell
division and host defence against Shigella infection. Although septin group members are …

Bacterial membrane vesicles from swine farm microbial communities harboring and safeguarding diverse functional genes promoting horizontal gene transfer

J Li, C Li, Y Han, J Yang, Y Hu, H Xu, Y Zhou… - Science of The Total …, 2024 - Elsevier
Antibiotic resistance (AMR) poses a significant global health challenge, with swine farms
recognized as major reservoirs of antibiotic resistance genes (ARGs). Recently, bacterial …

Shigella Induces Pro-Inflammatory Macrophages that Cooperate with Neutrophils to Protect from Secondary Infection

MC Gomes, D Brokatzky, S Mostowy - Available at SSRN 4981730, 2024 - papers.ssrn.com
Shigella is an important human pathogen for which there is no effective vaccine. Although
decades of seminal work have shown that pathogenicity of Shigella relies on induction of …