Rab proteins in fish and crustaceans: an overview

L Zhu, Y Gu, Y Kong, X Wang, H Li, L Hou… - Reviews in Fish Biology …, 2024 - Springer
The Rab family of proteins is involved in organelle regulation, trafficking, signal transduction,
mitosis, phagocytosis, growth differentiation, cytoskeleton protein depolymerization and …

Molecular characterization of Rab7 and its involvement in innate immunity in red swamp crayfish Procambarus clarkii

L Zhu, G Yuan, X Wang, T Zhao, L Hou, C Li… - Fish & Shellfish …, 2022 - Elsevier
Rab7 is a member of the Rab GTPases protein family, and it plays an essential role in
regulating trafficking organelles in higher animals. However, recent studies showed that it …

Ferritin Is Secreted from Primary Cultured Astrocyte in Response to Iron Treatment via TRPML1-Mediated Exocytosis

X Yu, Z Xiao, J Xie, H Xu - Cells, 2023 - mdpi.com
Impaired iron homeostasis has been proven to be one of the critical contributors to the
pathology of Parkinson's disease (PD). Ferritin is considered an intracellular protein …

Evidence of the Autophagic Process during the Fish Immune Response of Skeletal Muscle Cells against Piscirickettsia salmonis

CA Valenzuela, M Azúa, CA Álvarez, P Schmitt… - Animals, 2023 - mdpi.com
Simple Summary In mammals, autophagy plays a fundamental role in the defense against
intracellular pathogens; however, in fish, this noncanonical function has not been described …

[HTML][HTML] Identification and molecular characterization of Rab7 form Yellow River Carp Cyprinus carpio

G Di, N Wang, X Shen, D Lan, Y Wu, X Kong… - Aquaculture Reports, 2023 - Elsevier
Rab7 is a small GTPase that regulates vesicular traffic from early to late endosomal stages
of the endocytic pathway. In this study, full-length cDNA sequences of Rab7 were cloned …

Fish Rhbdd3 positively regulates IFN response through RIG-I signaling pathway

L Shao, M Zhang, Y Liu, J Peng, X Zhang… - Fish & Shellfish …, 2023 - Elsevier
Rhomboid domain-containing protein 3 (Rhbdd3) is a member of the rhomboid family, which
can modulate the innate immune response in mammals. Nonetheless, the function and …

Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis

D Pérez-Stuardo, A Espinoza, S Tapia… - Frontiers in …, 2020 - frontiersin.org
Piscirickettsia salmonis, an aggressive intracellular pathogen, is the etiological agent of
salmonid rickettsial septicemia (SRS). This is a chronic multisystemic disease that generates …

Salmonid alphavirus non-structural protein 2 is a key protein that activates the NF-κB signaling pathway to mediate inflammatory responses

S Gao, X Liu, B Han, N Wang, X Lv, X Guan… - Fish & Shellfish …, 2022 - Elsevier
Salmonid alphavirus (SAV) infection of Atlantic salmon (Salmo salar) and rainbow trout
(Oncorhynchus mykiss) causes pancreas disease (PD) with typical inflammatory responses …

Transgenic Rodent Models in Toxicological and Environmental Research: Future Perspectives

PV Christapher, T Ganeson, SV Chinni… - Journal of …, 2022 - journals.sagepub.com
The coexistence of humans and animals has existed for centuries. Over the past decade,
animal research has played a critical role in drug development and discovery. More and …

Ikke-klassiske MHC klasse I L-linjegener i atlantisk laks (Salmo salar)-Potensiell funksjonell rolle som tidlige antivirale varslingssignaler

E Mortensen - 2022 - munin.uit.no
The Atlantic salmon farming industry is constantly growing in Norway and if managed
properly can present a viable solution to the constantly increasing food demand resulting …