Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives

R Lordan, A Tsoupras, I Zabetakis, CA Demopoulos - Molecules, 2019 - mdpi.com
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced
histamine release from rabbit platelets producing antibodies in passive cutaneous …

Inflammation and cardiovascular disease: are marine phospholipids the answer?

R Lordan, S Redfern, A Tsoupras, I Zabetakis - Food & function, 2020 - pubs.rsc.org
Since the discovery that Greenlandic Innuits had a lower risk of developing cardiovascular
diseases (CVD) due to their diet of fish and as a consequence high polyunsaturated fatty …

Natural biomaterials from biodiversity for healthcare applications

E Insuasti‐Cruz, V Suárez‐Jaramillo… - Advanced …, 2022 - Wiley Online Library
Natural biomaterials originating during the growth cycles of all living organisms have been
used for many applications. They span from bioinert to bioactive materials including …

Cardiovascular diseases and marine oils: a focus on omega-3 polyunsaturated fatty acids and polar lipids

C Caffrey, A Leamy, E O'Sullivan, I Zabetakis, R Lordan… - Marine Drugs, 2023 - mdpi.com
Cardiovascular diseases (CVD) remain the leading cause of death across the globe, hence,
establishing strategies to counteract CVD are imperative to reduce mortality and the burden …

Identification and quantification of lipids in wild and farmed Atlantic salmon (Salmo salar), and salmon feed by GC‐MS

E Molversmyr, HM Devle… - Food Science & …, 2022 - Wiley Online Library
The fatty acid profiles of wild and farmed Atlantic salmon (Salmo salar) and salmon feed was
elucidated and quantitated. Due to the increasing proportion of vegetable oils in salmon …

Bioactive Lipids of Marine Microalga Chlorococcum sp. SABC 012504 with Anti-Inflammatory and Anti-Thrombotic Activities

K Shiels, A Tsoupras, R Lordan, C Nasopoulou… - Marine drugs, 2021 - mdpi.com
Microalgae are at the start of the food chain, and many are known producers of a significant
amount of lipids with essential fatty acids. However, the bioactivity of microalgal lipids for anti …

Antithrombotic properties of Spirulina extracts against platelet-activating factor and thrombin

P Koukouraki, A Tsoupras, G Sotiroudis… - Food Bioscience, 2020 - Elsevier
Spirulina (Arthrospira maxima) components have shown several health-benefits, including
immunomodulatory and anti-inflammatory properties. Even though a few studies have …

[HTML][HTML] The potential role of dietary platelet-activating factor inhibitors in cancer prevention and treatment

R Lordan, A Tsoupras, I Zabetakis - Advances in nutrition, 2019 - Elsevier
Cancer is the second leading cause of mortality worldwide. The role of unresolved
inflammation in cancer progression and metastasis is well established. Platelet-activating …

Fatty Acid Profile, Physicochemical Composition, and Sensory Properties of Atlantic Salmon Fish (Salmo salar) during Different Culinary Treatments

NS Fomena Temgoua, Z Sun, CO Okoye… - Journal of Food …, 2022 - Wiley Online Library
This study was conducted to assess the effects of boiling, steaming, and oven‐cooking on
the fatty acid profile, physicochemical composition, and sensory properties of Atlantic …

[HTML][HTML] Platelet aggregometry assay for evaluating the effects of platelet agonists and antiplatelet compounds on platelet function in vitro

A Tsoupras, I Zabetakis, R Lordan - MethodsX, 2019 - Elsevier
Platelet aggregometry assays are generally used for the analysis of platelet function but can
also be adapted for further research and therapy focused applications. This method …