In nearly half of the heart valve replacement surgeries performed annually, surgeons prefer
to implant bileaflet mechanical heart valves (BMHV) because of their durability and long life …

Experimental flow field characterization is a critical component of the assessment of the
hemolytic and thrombogenic potential of heart valve substitutes, thus it is important to identify …

We present comprehensive particle image velocimetry measurements and direct numerical
simulation (DNS) of physiological, pulsatile flow through a clinical quality bileaflet …

This study is part of a FDA-sponsored project to evaluate the use and limitations of
computational fluid dynamics (CFD) in assessing blood flow parameters related to medical …

The wall shear stress induced by the leaflet motion during the valve-closing phase has been
implicated with thrombus initiation with prosthetic valves. Detailed flow dynamic analysis in …

We have performed high-resolution fluid–structure interaction simulations of physiologic
pulsatile flow through a bi-leaflet mechanical heart valve (BMHV) in an anatomically realistic …

Bileaflet mechanical heart valves (BMHVs) are prone to thromboembolic complications
which are believed to be initiated by platelet activation. Platelets are activated by non …

Cavitation was first directly related to mechanical heart valves in the mid 1980s after a series
of valve failures observed with the Edwards–Duromedics valve. The damages observed …

Computational simulations are playing an increasingly important role in enhancing our
understanding of the normal human physiological function, etiology of diseased states …

An experimental set-up is presented for the in vitro characterization of the fluid dynamics in
personalized phantoms of healthy and stenosed coronary arteries. The proposed set-up was …