Oral squamous cell carcinoma (OSCC) is the most common type of head and neck cancers.
OSCC constitutes 90% of the head and neck malignancies. The delayed identification of oral …

Cyclin D1 has been reported to be upregulated in several solid and hematologic tumors,
promoting cancer progression. Thus, decreasing cyclin D1 by degradation could be a …

Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive subtype of
kidney cancer, with high mortality rates worldwide. The sonic hedgehog (SHH) molecular …

Metabolic remodeling is the fundamental molecular feature of malignant tumors. Cancer
cells require sufficient energy supplies supporting their high proliferative rate. MTHFD2, a …

The relevance of cyclin D1 (CCND1) has been implicated in lung cancer progression.
Nevertheless, the mechanism by which CCND1 supports lung cancer development is yet to …

We investigated the prognostic influences of BCL1 and BCL2 expression on disease-free
survival in breast cancer patients. BCL1 and BCL2 expression statuses were assessed by …

Abstract microRNA are noncoding endogenous RNAs of∼ 25-nucleotide, involved in RNA
silencing and controlling of cell function. Recent evidence has highlighted the important role …

Colon adenocarcinoma (COAD) is among the most common digestive system malignancies
worldwide, and its pathogenesis and gene signatures remain unclear. This study explored …

The aim of this study was to determine, by immunohistochemical methods, the expression of
nEGFR and markers of cell proliferation (Ki-67), cell cycle (mEGFR, p53, cyclin D1), and …

Simple Summary Although immunohistochemistry is a routine technique in clinics, and
genomics has been rapidly incorporated, proteomics is a step behind. This general situation …