The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers
Q Zhang, Y Zhu, X Cao, W Tan, J Yu, Y Lu, R Kang… - Molecular Cancer, 2023 - Springer
PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are
significant in development and reproduction of organisms. Recently, emerging evidences …
significant in development and reproduction of organisms. Recently, emerging evidences …
[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation
DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
Global DNA hypomethylation in epithelial ovarian cancer: passive demethylation and association with genomic instability
A hallmark of human cancer is global DNA hypomethylation (GDHO), but the mechanisms
accounting for this defect and its pathological consequences have not been investigated in …
accounting for this defect and its pathological consequences have not been investigated in …
Non-coding RNAs, epigenetics, and cancer: tying it all together
HJ Ferreira, M Esteller - Cancer and Metastasis Reviews, 2018 - Springer
While only a small part of the human genome encodes for proteins, biological functions for
the so-called junk genome are increasingly being recognized through high-throughput …
the so-called junk genome are increasingly being recognized through high-throughput …
PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma
Altered energy metabolism of cancer cells shapes the immune cell response in the tumor
microenvironment that facilitates tumor progression. Herein, we reported the novel of tumor …
microenvironment that facilitates tumor progression. Herein, we reported the novel of tumor …
The emerging roles of PIWI-interacting RNA in human cancers
Y Yu, J Xiao, SS Hann - Cancer Management and Research, 2019 - Taylor & Francis
PIWI-interacting RNAs (piRNAs) are a type of non-coding RNAs that interact with PIWI
proteins, which are members of the argonaute family. Originally described in the germline …
proteins, which are members of the argonaute family. Originally described in the germline …
PIWI-RNAs Small Noncoding RNAs with Smart Functions: Potential Theranostic Applications in Cancer
S Taverna, A Masucci, G Cammarata - Cancers, 2023 - mdpi.com
Simple Summary P-element-induced wimpy testis-interacting RNAs (piRNAs) are a novel
class of small regulatory RNAs that often bind to PIWI proteins. First identified in animal germ …
class of small regulatory RNAs that often bind to PIWI proteins. First identified in animal germ …
Noncoding RNAs: new players in cancers
X Chen, S Fan, E Song - The Long and Short Non-coding RNAs in Cancer …, 2016 - Springer
The world of noncoding RNAs (ncRNAs) has gained widespread attention in recent years
due to their novel and crucial potency of biological regulation. Noncoding RNAs play …
due to their novel and crucial potency of biological regulation. Noncoding RNAs play …
[HTML][HTML] Epigenetic dynamics and interplay during spermatogenesis and embryogenesis: implications for male fertility and offspring health
SQ Ge, SL Lin, ZH Zhao, QY Sun - Oncotarget, 2017 - ncbi.nlm.nih.gov
Mapping epigenetic modifications and identifying their roles in the regulation of
spermatogenesis and embryogenesis are essential for gaining fundamental medical …
spermatogenesis and embryogenesis are essential for gaining fundamental medical …
Between a rock and a hard place: an epigenetic-centric view of testicular germ cell tumors
Simple Summary This minireview focuses on the role of epigenetics in testicular cancer. A
working model is developed that postulates that epigenetic features that drive testicular …
working model is developed that postulates that epigenetic features that drive testicular …