Studies of human tumors by MRS: a review

W Negendank - NMR in Biomedicine, 1992 - Wiley Online Library
The literature describing 31P, 1H, 13C, 23Na and 19F MRS in vivo in human cancers is
reviewed. Cancers have typical metabolic characteristics in 31P and 1H MRS including high …

[PDF][PDF] Clinical applications of proton MR spectroscopy.

M Castillo, L Kwock… - Ajnr: American Journal of …, 1996 - Am Soc Neuroradiology
Magnetic resonance (MR) spectroscopy has received little attention from the clinical
radiology community. Indeed, most MR spectroscopic studies are performed by a small and …

Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging

M Law, S Yang, H Wang, JS Babb… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Sensitivity, positive predictive value (PPV), and negative
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high …

Preoperative proton MR spectroscopic imaging of brain tumors: correlation with histopathologic analysis of resection specimens

C Dowling, AW Bollen, SM Noworolski… - American journal …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Tumor progression is often difficult to distinguish from
nonneoplastic treatment response on the basis of MR images alone. This study correlates …

High Speed 1H Spectroscopic Imaging in Human Brain by Echo Planar Spatial‐Spectral Encoding

S Posse, G Tedeschi, R Risinger… - Magnetic resonance …, 1995 - Wiley Online Library
We introduce a fast and robust spatial‐spectral encoding method, which enables acquisition
of high resolution short echo time (13 ms) proton spectroscopic images from human brain …

Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance.

MJ Fulham, A Bizzi, MJ Dietz, HH Shih, R Raman… - Radiology, 1992 - pubs.rsna.org
Brain tumor metabolism was studied with hydrogen-1 magnetic resonance spectroscopy
and positron emission tomography with fluorine-18 fluorodeoxyglucose in 50 patients. N …

Distinction between high-grade gliomas and solitary metastases using peritumoral 3-T magnetic resonance spectroscopy, diffusion, and perfusion imagings

IC Chiang, YT Kuo, CY Lu, KW Yeung, WC Lin… - Neuroradiology, 2004 - Springer
This study compared the effectiveness of relative cerebral blood volume, apparent diffusion
coefficient, and spectroscopic imaging in differentiating between primary high-grade gliomas …

Multisection proton MR spectroscopic imaging of the brain.

JH Duyn, J Gillen, G Sobering, PC Van Zijl, CT Moonen - Radiology, 1993 - pubs.rsna.org
The authors developed a hydrogen-1 proton magnetic resonance (MR) imaging method in
which metabolic information is acquired by obtaining multiple sections through the brain. A …

MR-spectroscopy guided target delineation for high-grade gliomas

A Pirzkall, TR McKnight, EE Graves, MP Carol… - International Journal of …, 2001 - Elsevier
Purpose: Functional/metabolic information provided by MR-spectroscopy (MRSI) suggests
MRI may not be a reliable indicator of active and microscopic disease in malignant brain …

Multivoxel magnetic resonance spectroscopy of brain tumors

SJ Nelson - Molecular cancer therapeutics, 2003 - AACR
Magnetic resonance spectroscopy (MRS) is becoming more widely available for clinical
applications and is able to provide information about the metabolic properties of regions of …