[HTML][HTML] Exosome-based nanoparticles and cancer immunotherapy

J Ye, D Li, Y Jie, H Luo, W Zhang, C Qiu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Over the past decades, cancer immunotherapy has encountered challenges such as
immunogenicity, inefficiency, and cytotoxicity. Consequently, exosome-based cancer …

Forging new therapeutic targets: efforts of tumor derived exosomes to prepare the pre-metastatic niche for cancer cell dissemination and dormancy

R Bhatia, J Chang, JL Munoz, ND Walker - Biomedicines, 2023 - mdpi.com
Tumor-derived exosomes play a multifaceted role in preparing the pre-metastatic niche,
promoting cancer dissemination, and regulating cancer cell dormancy. A brief review of …

Neoantigen sequestrated autophagosomes as therapeutic cancer vaccines

J Zhang, J Cao, L Wang, S Li, F Meng, X Liang… - Journal of Controlled …, 2024 - Elsevier
Neoantigens serve as ideal personalized cancer vaccines because of their high
immunogenicity, ability to evade central thymic tolerance, and minimal risk of eliciting …

Nanocarrier-Mediated Immunogenic Cell Death for Melanoma Treatment

J Wang, J Ma, Z Tai, L Li, T Zhang… - International Journal …, 2023 - Taylor & Francis
Melanoma, a highly aggressive skin tumor, exhibits notable features including
heterogeneity, a high mutational load, and innate immune escape. Despite advancements in …

Oncolytic Viruses in Cancer Immunotherapy

X Li, Z Cheng - Advanced Therapeutics, 2024 - Wiley Online Library
Oncolytic viruses are novel and promising therapeutic regimens that promote antitumor
efficacy through multimode mechanisms, including direct lysis of tumor cells, release of the …

[HTML][HTML] Functional engineered exosomes mitigate pathological ischemic retinopathy through a dual strategy of inflammatory microenvironment modulation and …

D Yan, F Yu, W Ouyang, J Hu, T Zhou, C Huang… - Materials & Design, 2023 - Elsevier
Retinal neovascularization (RNV), a major cause of blindness, is usually treated with anti-
VEGF drugs. Despite successes, incomplete patient responses push for alternative …

Stromal and tumor immune microenvironment reprogramming through multifunctional cisplatin-based liposomes boosts the efficacy of anti-PD-1 immunotherapy in …

H Yu, W Zhu, C Lin, M Jia, X Tan, Z Yuan, S Feng… - Biomaterials …, 2024 - pubs.rsc.org
The dense stromal barrier in pancreatic cancer tissues blocks intratumoral delivery and
distribution of chemotherapeutics and therapeutic antibodies, causing poor …

Nanomedicine Targeting Myeloid‐Derived Suppressor Cells Enhances Anti‐Tumor Immunity

EL Yang, ZJ Sun - Advanced Healthcare Materials, 2024 - Wiley Online Library
Cancer immunotherapy, a field within immunology that aims to enhance the host's anti‐
cancer immune response, frequently encounters challenges associated with suboptimal …

Progress of mesoporous silica coated gold nanorods for biological imaging and cancer therapy

J Ma, Y Li, Y Ying, B Wu, Y Liu, J Zhou, L Hu - Chemmedchem, 2024 - Wiley Online Library
For unique surface plasmon absorption and fluorescence characteristics, gold nanorods
have been developed and widely employed in the biomedical field. However, limitations still …

[HTML][HTML] New opportunities of stimulus-responsive smart nanocarriers in cancer therapy

X Liu, F He, M Liu - Nano Materials Science, 2024 - Elsevier
Achieving precise delivery has always been a key challenge in the development of
nanomedicine to treat cancer. Intelligent stimulus-responsive nanocarriers imbued with …