Plant lipids: Key players of plasma membrane organization and function

AM Cassim, P Gouguet, J Gronnier, N Laurent… - Progress in Lipid …, 2019 - Elsevier
The plasma membrane (PM) is the biological membrane that separates the interior of all
cells from the outside. The PM is constituted of a huge diversity of proteins and lipids. In this …

GM1 ganglioside is a key factor in maintaining the mammalian neuronal functions avoiding neurodegeneration

E Chiricozzi, G Lunghi, E Di Biase, M Fazzari… - International journal of …, 2020 - mdpi.com
Many species of ganglioside GM1, differing for the sialic acid and ceramide content, have
been characterized and their physico-chemical properties have been studied in detail since …

Roles of ceramides and other sphingolipids in immune cell function and inflammation

S Albeituni, J Stiban - The Role of Bioactive Lipids in Cancer, Inflammation …, 2019 - Springer
Ceramides are bioactive sphingolipids that support the structure of the plasma membrane
and mediate numerous cell-signaling events in eukaryotic cells. The finding that ceramides …

Role of lipid rafts in pathogen-host interaction-a mini review

R Kulkarni, EAC Wiemer, W Chang - Frontiers in Immunology, 2022 - frontiersin.org
Lipid rafts, also known as microdomains, are important components of cell membranes and
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …

Divide and rule: plant plasma membrane organization

J Gronnier, P Gerbeau-Pissot, V Germain… - Trends in plant …, 2018 - cell.com
Since the publication of the fluid mosaic as a relevant model for biological membranes,
accumulating evidence has revealed the outstanding complexity of the composition and …

The impact of dietary sphingolipids on intestinal microbiota and gastrointestinal immune homeostasis

J Rohrhofer, B Zwirzitz, E Selberherr… - Frontiers in …, 2021 - frontiersin.org
The large surfaces of gastrointestinal (GI) organs are well adapted to their diverse tasks of
selective nutritional uptake and defense against the external environment. To maintain a …

Glyco-gold nanoparticles: synthesis and applications

F Compostella, O Pitirollo, A Silvestri… - Beilstein journal of …, 2017 - beilstein-journals.org
Glyco-gold nanoparticles combine in a single entity the peculiar properties of gold
nanoparticles with the biological activity of carbohydrates. The result is an exciting …

The regulatory roles of glycosphingolipid‐enriched lipid rafts in immune systems

H Nakayama, M Nagafuku, A Suzuki, K Iwabuchi… - FEBS …, 2018 - Wiley Online Library
Lipid rafts formed by glycosphingolipids (GSLs) on cellular membranes play important roles
in innate and adaptive immunity. Lactosylceramide (LacCer) forms lipid rafts on plasma and …

Role of the GM 1 ganglioside oligosaccharide portion in the TrkA‐dependent neurite sprouting in neuroblastoma cells

E Chiricozzi, DY Pomè, M Maggioni… - Journal of …, 2017 - Wiley Online Library
Abstract GM 1 ganglioside (II 3NeuAc‐Gg4Cer) is known to promote neurite formation in
neuroblastoma cells by activating TrkA‐MAPK pathway. The molecular mechanism by which …

Synthetic strategies for modified glycosphingolipids and their design as probes

CD Hunter, T Guo, G Daskhan, MR Richards… - Chemical …, 2018 - ACS Publications
The plasma membrane of cells contains a diverse array of lipids that provide important
structural and biological features. Glycolipids are typically a minor component of the cell …