Open questions in the NF-κB field

S Bacher, ML Schmitz - Biochimica et Biophysica Acta (BBA)-Molecular …, 2024 - Elsevier
A variety of stress signals leads to activation of the inducible transcription factor NF-κB, one
of the master regulators of the innate immune response. Despite a wealth of information …

An innate ability: How do basal invertebrates manage their chronic exposure to microbes?

LM Williams, TD Gilmore - PLoS Pathogens, 2022 - journals.plos.org
Homologs of mammalian innate immune sensing and downstream pathway proteins have
been discovered in a variety of basal invertebrates, including cnidarians and sponges, as …

Control of nuclear localization of the nucleocapsid protein of SARS-CoV-2

M Wang, M Valadez-Ingersoll, TD Gilmore - Virology, 2024 - Elsevier
The nucleocapsid (N) protein of coronaviruses is a structural protein that binds viral RNA for
assembly into the mature virion, a process that occurs in the cytoplasm. Several coronavirus …

The first embryo, the origin of cancer and animal phylogeny. IV. The neoplastic basis for the formation of the innate immune system

J Cofre - Frontiers in Ecology and Evolution, 2024 - frontiersin.org
The formation of the innate immune system of animals can only be envisioned after the
development of the first metazoan embryo. The decisive role of Embryology in …