Oxidative stress involves the increased production and accumulation of free radicals,
peroxides, and other metabolites that are collectively termed reactive oxygen species (ROS) …

Purpose Deinococcus radiodurans is an extremely radioresistant bacterium characterized
by D10 of 10 kGy, and able to grow luxuriantly under chronic ionizing radiation of 60 Gy/h …

The thioredoxin (Trx) system, found universally, is responsible for the regeneration of
reversibly oxidized protein thiols in living cells. This system is made up of a Trx and a Trx …

Heavy ion radiotherapy is an effective treatment for tumors, but its therapeutic efficacy is
limited in cancer cells with radiation resistance. Deinococcus radiodurans, well known for its …

Deinococcus species possess remarkable tolerance to extreme environmental conditions
that generate oxidative damage to macromolecules. Among enzymes fulfilling key functions …

This paper reports the results of gamma irradiation experiments and whole genome
sequencing (WGS) performed on vegetative cells of two radiation resistant bacterial strains …

The thioredoxin-like protein exists widely, in various organisms, as a regulator of redox
homeostasis. In this study, the full-length cDNA of a thioredoxin-like protein gene from rotifer …

Simple Summary This article reviews the biological importance of the Thioredoxin-1 system
in different cells and organs. Redox balance, defined by an equilibrium between oxidized …

Thioredoxin (Trx) is essential in a redox-control system, with many bacteria containing two
Trxs: Trx1 and Trx2. Due to a Trx system's critical function, Trxs are targets for novel …

Abstract Background Polysaccharides derived from Aralia continentalis Kitagawa possess
excellent biological properties, such as anti-tumor, antioxidant, antibacterial, lipid-lowering …