Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Bioconjugated oligonucleotides: recent developments and therapeutic applications

S Benizri, A Gissot, A Martin, B Vialet… - Bioconjugate …, 2019 - ACS Publications
Oligonucleotide-based agents have the potential to treat or cure almost any disease, and
are one of the key therapeutic drug classes of the future. Bioconjugated oligonucleotides, a …

Rational design, properties, and applications of biosurfactants: a short review of recent advances

K Liu, Y Sun, M Cao, J Wang, JR Lu, H Xu - Current Opinion in Colloid & …, 2020 - Elsevier
Biosurfactants combine physicochemical properties with biological activities. Although
biosurfactants are often expressed by microorganisms, an increasing amount is produced by …

An efficient and modular route to sequence‐defined polymers appended to DNA

TGW Edwardson, KMM Carneiro… - Angewandte Chemie …, 2014 - Wiley Online Library
Inspired by biological polymers, sequence‐controlled synthetic polymers are highly
promising materials that integrate the robustness of synthetic systems with the information …

Nucleic acid amphiphiles: synthesis, properties, and applications

A Gubu, X Zhang, A Lu, B Zhang, Y Ma… - … Therapy-Nucleic Acids, 2023 - cell.com
Nucleic acid amphiphiles, referring to nucleic acids modified with large hydrophobic groups,
have been widely used in programmable bioengineering. Since nucleic acids are …

The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo

A Biscans, A Coles, D Echeverria… - Journal of controlled …, 2019 - Elsevier
Lipid-conjugated small-interfering RNAs (siRNAs) exhibit accumulation and gene silencing
in extrahepatic tissues, providing an opportunity to expand therapeutic siRNA utility beyond …

[HTML][HTML] pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin

MC García, JM Calderón-Montaño, M Rueda… - International journal of …, 2022 - Elsevier
Liposomes (Lip) are useful nanocarriers for drug delivery and cancer nanomedicine
because of their ability to efficiently encapsulate drugs with different physical and chemical …

DNA− π amphiphiles: a unique building block for the crafting of DNA-decorated unilamellar nanostructures

SK Albert, M Golla, N Krishnan, D Perumal… - Accounts of Chemical …, 2020 - ACS Publications
Conspectus The unparalleled ability of DNA to recognize its complementary strand through
Watson and Crick base pairing is one of the most reliable molecular recognition events …

Lipid nanoparticles for RNA delivery: Self-assembling vs driven-assembling strategies

V Nele, V Campani, SA Moosavian… - Advanced Drug Delivery …, 2024 - Elsevier
Among non-viral vectors, lipid nanovectors are considered the gold standard for the delivery
of RNA therapeutics. The success of lipid nanoparticles for RNA delivery, with three products …

[HTML][HTML] Lipid-oligonucleotide conjugates improve cellular uptake and efficiency of TCTP-antisense in castration-resistant prostate cancer

S Karaki, S Benizri, R Mejías, V Baylot… - Journal of Controlled …, 2017 - Elsevier
Translationally controlled tumor protein (TCTP) has been implicated in a plethora of
important cellular processes related to cell growth, cell cycle progression, malignant …