Adsorption of gut relevant biomolecules onto particles after oral administration of solid oral
dosage forms is expected to form a “gastrointestinal corona”, which could influence solution …

The critical cooling rate (CRcrit) to prevent drug crystallization during the preparation of
nifedipine amorphous solid dispersions (ASDs) was determined through the time …

Bile salt based low-molecular-weight supramolecular hydrogels (LMWSH) serve as an
appealing framework for drug delivery applications, owing to their natural origin …

Co-amorphous (CA) formulation is a promising strategy to improve the solubility of poorly
water-soluble drugs, however, effective prediction of a CA system is a challenge. In this …

In this work, the co-amorphization approach was applied to flubendazole (FluBZ), resulting
in the formation of two novel solid forms of FluBZ with l-phenylalanine (Phe) and l-tryptophan …

Although lipid‐based formulations are an attractive approach for enhancing the oral
bioavailability of lipophilic drugs, their addition into solid oral dosage forms has been proven …

Drugs with poor water and lipid solubility are termed “brick dust.” We previously successfully
developed a co-amorphous system of a novel neuropeptide Y 5 receptor antagonist (AntiY 5 …

Brick dust molecules are usually poorly soluble in water and lipoidal components, making it
difficult to formulate them in dosage forms that provide efficient pharmacological effects. A co …