Poloxamer: A versatile tri-block copolymer for biomedical applications

P Zarrintaj, JD Ramsey, A Samadi, Z Atoufi, MK Yazdi… - Acta biomaterialia, 2020 - Elsevier
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Recent advances in nanoparticle-based cancer drug and gene delivery

N Amreddy, A Babu, R Muralidharan… - Advances in cancer …, 2018 - Elsevier
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …

Review of applications and future prospects of stimuli-responsive hydrogel based on thermo-responsive biopolymers in drug delivery systems

S Chatterjee, PC Hui - Polymers, 2021 - mdpi.com
Some of thermo-responsive polysaccharides, namely, cellulose, xyloglucan, and chitosan,
and protein-like gelatin or elastin-like polypeptides can exhibit temperature dependent sol …

Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review

P Singla, S Garg, J McClements, O Jamieson… - Advances in Colloid and …, 2022 - Elsevier
Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …

Biomimetic nanoparticles to enhance the reverse cholesterol transport for selectively inhibiting development into foam cell in atherosclerosis

L Zhu, H Li, J Li, Y Zhong, S Wu, M Yan, S Ni… - Journal of …, 2023 - Springer
A disorder of cholesterol homeostasis is one of the main initiating factors in the progression
of atherosclerosis (AS). Metabolism and removal of excess cholesterol facilitates the …

Influence of pH-responsive compounds synthesized from chitosan and hyaluronic acid on dual-responsive (pH/temperature) hydrogel drug delivery systems of Cortex …

S Chatterjee, PC Hui, WS Siu, C Kan, PC Leung… - International Journal of …, 2021 - Elsevier
The polysaccharide-based pH-responsive compounds, namely, N, N, N-trimethyl chitosan
(TMC), polyethylene glycolated hyaluronic acid (PEG-HA), and polysaccharide-based nano …

Drug delivery system of dual-responsive PF127 hydrogel with polysaccharide-based nano-conjugate for textile-based transdermal therapy

S Chatterjee, PCL Hui, E Wat, C Kan, PC Leung… - Carbohydrate …, 2020 - Elsevier
Pluronic F-127 based dual-responsive (pH/temperature) hydrogel drug delivery system was
developed involving polysaccharide-based nano-conjugate of hyaluronic acid and chitosan …

Self-healing of Pluronic® F127 hydrogels in the presence of various polysaccharides

A Lupu, LM Gradinaru, D Rusu, M Bercea - Gels, 2023 - mdpi.com
Thermoresponsive Pluronic® F127 (PL) gels in water were investigated through rheological
tests in different shear conditions. The gel strength was tuned with the addition of 1 …

[HTML][HTML] Development and characterization of a poloxamer hydrogel composed of human mesenchymal stromal cells (hMSCs) for reepithelization of skin injuries

C Galocha-León, C Antich, A Voltes-Martínez… - International Journal of …, 2023 - Elsevier
Wound healing is a natural physiological reaction to tissue injury. Hydrogels show attractive
advantages in wound healing not only due to their biodegradability, biocompatibility and …

Temperature induced gelation and antimicrobial properties of Pluronic F127 based systems

A Lupu, I Rosca, VR Gradinaru, M Bercea - Polymers, 2023 - mdpi.com
Different formulations containing Pluronic F127 and polysaccharides (chitosan, sodium
alginate, gellan gum, and κ-carrageenan) were investigated as potential injectable gels that …