Healthy effects of plant polyphenols: molecular mechanisms

M Leri, M Scuto, ML Ontario, V Calabrese… - International journal of …, 2020 - mdpi.com
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

Olive polyphenols: Antioxidant and anti-inflammatory properties

M Bucciantini, M Leri, P Nardiello, F Casamenti… - Antioxidants, 2021 - mdpi.com
Oxidative stress and inflammation triggered by increased oxidative stress are the cause of
many chronic diseases. The lack of anti-inflammatory drugs without side-effects has …

Therapeutics of Alzheimer's disease: Past, present and future

R Anand, KD Gill, AA Mahdi - Neuropharmacology, 2014 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases

S Bulotta, M Celano, SM Lepore, T Montalcini… - Journal of translational …, 2014 - Springer
The overall health beneficial action of olive oil phenolic components is well established.
Recent studies have elucidated the biological effects of two isolated compounds, namely …

Influence of the Mediterranean diet on healthy aging

MC Andreo-López, V Contreras-Bolívar… - International Journal of …, 2023 - mdpi.com
The life expectancy of the global population has increased. Aging is a natural physiological
process that poses major challenges in an increasingly long-lived and frail population …

Traditional Uses, Phytochemistry, and Pharmacology of Olea europaea (Olive)

MA Hashmi, A Khan, M Hanif, U Farooq… - Evidence‐Based …, 2015 - Wiley Online Library
Aim of the Review. To grasp the fragmented information available on the botany, traditional
uses, phytochemistry, pharmacology, and toxicology of Olea europaea to explore its …

Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies

S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Effects of the olive-derived polyphenol oleuropein on human health

B Barbaro, G Toietta, R Maggio, M Arciello… - International journal of …, 2014 - mdpi.com
The use of the products derived from the olive tree on human health dates back centuries. In
several civilizations, the olive tree had and still has a very strong cultural and religious …

Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans

S Rigacci, M Stefani - International journal of molecular sciences, 2016 - mdpi.com
The increasing interest in the Mediterranean diet hinges on its healthy and anti-ageing
properties. The composition of fatty acids, vitamins and polyphenols in olive oil, a key …

Identification of the Tau phosphorylation pattern that drives its aggregation

C Despres, C Byrne, H Qi… - Proceedings of the …, 2017 - National Acad Sciences
Determining the functional relationship between Tau phosphorylation and aggregation has
proven a challenge owing to the multiple potential phosphorylation sites and their clustering …