Background: Dentin is a permeable tubular composite and complex structure, and in weight,
it is composed of 20% organic matrix, 10% water, and 70% hydroxyapatite crystalline matrix …

Tissue regeneration is a vital phenomenon in the skeletal system of human beings during
their life span. The structure of bony architecture and teeth are highly dependent to this …

Demineralized dentin matrix (DDM)-based materials have been actively developed and are
well-known for their excellent performance in dental tissue regeneration. However, DDM …

Dental pulp stem cells constitute an attractive source of multipotent mesenchymal stem cells
owing to their high proliferation rate and multilineage differentiation potential. Osteogenesis …

Root canal therapy has enabled us to save numerous teeth over the years. The most desired
outcome of endodontic treatment would be when diseased or nonvital pulp is replaced with …

In the last few decades, biomimetic concepts have been widely adopted in various
biomedical fields, including clinical dentistry. Endodontics is an important sub-branch of …

Following the basis of tissue engineering (Cells–Scaffold–Bioactive molecules),
regenerative endodontic has emerged as a new concept of dental treatment. Clinical …

Currently, the principal strategy for the treatment of carious defects involves cavity
preparations followed by the restoration of natural tooth structure with a synthetic material of …

Tissue engineering is a new therapeutic strategy used to repair serious damage caused by
trauma, a tumor or other major diseases, either for vital organs or tissues sited in the oral …

Dentine matrix has proposed roles for directing mineralised tissue repair in dentine and
bone; however, the range of bioactive components in dentine and specific biological effects …