Changing views on the common physiologic abnormality that mediates salt sensitivity and initiation of salt-induced hypertension: Japanese research underpinning the …

TW Kurtz, SE DiCarlo, M Pravenec, RC Morris - Hypertension Research, 2019 - nature.com
High-salt intake is one of the major dietary determinants of increased blood pressure and
cardiovascular disease. Thus, there is scientific and medical interest in understanding the …

Enhanced antioxidative defense by vitamins C and E consumption prevents 7-day high-salt diet-induced microvascular endothelial function impairment in young …

L Barić, I Drenjančević, M Mihalj, A Matić… - Journal of clinical …, 2020 - mdpi.com
This study aimed to examine whether the oral supplementation of vitamins C and E during a
seven-day high salt diet (HS;~ 14 g salt/day) prevents microvascular endothelial function …

Tff3−/− Knock-Out Mice with Altered Lipid Metabolism Exhibit a Lower Level of Inflammation following the Dietary Intake of Sodium Chloride for One Week

N Kolobarić, M Mihalj, N Kozina, A Matić… - International journal of …, 2023 - mdpi.com
A high salt intake causes hemodynamic changes and promotes immune response through
cell activation and cytokine production, leading to pro-inflammatory conditions. Transgenic …

Leukocyte Activation and Antioxidative Defense Are Interrelated and Moderately Modified by n-3 Polyunsaturated Fatty Acid-Enriched Eggs Consumption—Double …

M Mihalj, A Stupin, N Kolobarić, I Tartaro Bujak, A Matić… - Nutrients, 2020 - mdpi.com
This placebo-controlled, double-blind, randomized, interventional study investigated the
effects of low/intermediate doses of n-3 polyunsaturated fatty acids (PUFAs) on the …

[HTML][HTML] Oral Carnosine Supplementation Preserves Vascular Function of Sprague Dawley Rats on a High-Salt Diet via Restored Antioxidative Defence

I Drenjančević, A Stupin, I Jukić, N Kolobarić… - Nutrients, 2024 - mdpi.com
Backgrounds/Objectives: Following previous findings on high-salt (HS)-intake-related
increase of oxidative stress, this study explored whether carnosine (CAR; β-alanyl-L …

Angiotensin II type 1 receptor is involved in flow-induced vasomotor responses of isolated middle cerebral arteries: Role of oxidative stress

I Jukic, Z Mihaljevic, A Matic, M Mihalj… - American Journal …, 2021 - journals.physiology.org
This study aimed to determine the mechanosensing role of angiotensin II type 1 receptor
(AT1R) in flow-induced dilation (FID) and oxidative stress production in middle cerebral …

Arachidonic acid metabolites of CYP450 enzymes and HIF-1α modulate endothelium-dependent vasorelaxation in Sprague-Dawley rats under acute and intermittent …

Z Mihaljević, A Matić, A Stupin, R Frkanec… - International journal of …, 2020 - mdpi.com
Acetylcholine-induced vasorelaxation (AChIR) and responses to reduced pO2 (hypoxia-
induced relaxation (HIR), 0% O2) were assessed in vitro in aortic rings of healthy male …

Impact of High Salt Diet on Cerebral Vascular Function and Stroke in Tff3−/−/C57BL/6N Knockout and WT (C57BL/6N) Control Mice

N Kozina, Z Mihaljević, M Baus Lončar… - International journal of …, 2019 - mdpi.com
High salt (HS) dietary intake leads to impaired vascular endothelium-dependent responses
to various physiological stimuli, some of which are mediated by arachidonic acid (AA) …

Short‐term high‐NaCL dietary intake changes leukocyte expression of VLA‐4, LFA‐1, and Mac‐1 integrins in both healthy humans and sprague‐dawley rats: a …

M Mihalj, A Matić, Z Mihaljević, L Barić… - Mediators of …, 2019 - Wiley Online Library
This study is aimed at assessing the effects of a short‐term high‐salt (HS) diet on the
peripheral blood leukocyte (PBL) activation status in healthy rats and young human …

The Effect of High-Salt Diet on Oxidative Stress Production and Vascular Function in Tff3−/−/C57BL/6N Knockout and Wild Type (C57BL/6N) Mice

N Kozina, I Jukić, Z Mihaljević, A Matić… - Journal of Vascular …, 2024 - karger.com
Introduction: It is well documented that high-salt (HS) diet increases systemic and vascular
oxidative stress in various animal models and in humans, leading to impairment of vascular …