Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup

A Zarbock, MK Nadim, P Pickkers, H Gomez… - Nature Reviews …, 2023 - nature.com
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

The proximal tubule as the pathogenic and therapeutic target in acute kidney injury

KM Ho, DJR Morgan - Nephron, 2022 - karger.com
Background: In 2004, the term acute kidney injury (AKI) was introduced with the intention of
broadening our understanding of rapid declines in renal function and to replace the …

The effect of low-dose furosemide in critically ill patients with early acute kidney injury: a pilot randomized blinded controlled trial (the SPARK study)

SM Bagshaw, RTN Gibney, P Kruger, I Hassan… - Journal of critical …, 2017 - Elsevier
Purpose Furosemide is commonly prescribed in acute kidney injury (AKI). Prior studies have
found conflicting findings on whether furosemide modifies the course and outcome of AKI …

Practical approach to detection and management of acute kidney injury in critically ill patient

V Mohsenin - Journal of intensive care, 2017 - Springer
Background Acute kidney injury (AKI) is a common complication in critically ill patients and is
associated with high morbidity and mortality. This paper provides a critical review of the …

Non-interventional follow-up versus fluid bolus in RESPONSE to oliguria in hemodynamically stable critically ill patients: a randomized controlled pilot trial

N Inkinen, V Pettilä, M Valkonen, M Serlo, M Bäcklund… - Critical Care, 2022 - Springer
Background Fluid bolus therapy is a common intervention to improve urine output. Data
concerning the effect of a fluid bolus on oliguria originate mainly from observational studies …

[HTML][HTML] Diuretic strategies in patients with resistance to loop-diuretics in the intensive care unit: A retrospective study from the MIMIC-III database

JM Cote, J Bouchard, PT Murray… - Journal of Critical …, 2021 - Elsevier
Purpose To investigate various diuretic strategies to alleviate loop-diuretics resistance in
critically ill patients. Materials and method ICU adults requiring more than 1 mg/kg/day of …

Impact of furosemide on mortality and the requirement for renal replacement therapy in acute kidney injury: a systematic review and meta-analysis of randomised trials

ŁJ Krzych, PF Czempik - Annals of Intensive Care, 2019 - Springer
Objective To examine the impact of furosemide on mortality and the need for renal
replacement therapy (RRT) in adult patients with acute kidney injury (AKI) based on current …

Furosemide as a functional marker of acute kidney injury in ICU patients: a new role for an old drug

F Mariano, A Mella, M Vincenti, L Biancone - Journal of nephrology, 2019 - Springer
New pharmacokinetics insight suggests that the furosemide pharmacology occurring in ICU
patients with AKI is similar, but not equal to that described in chronic stable renal patients …

Patterns of diuretic use in the intensive care unit

IE McCoy, GM Chertow, TIH Chang - PloS one, 2019 - journals.plos.org
Purpose To inform future outcomes research on diuretics, we sought to describe modern
patterns of diuretic use in the intensive care unit (ICU), including diuretic type, combination …

Does furosemide increase oxidative stress in acute kidney injury?

BI Silbert, KM Ho, J Lipman, JA Roberts, TB Corcoran… - 2017 - liebertpub.com
Furosemide, a loop diuretic, is used to increase urine output in patients with acute kidney
injury (AKI). It remains uncertain whether the benefits of furosemide in AKI outweigh its …