In vitro selection of aptamers and their applications

MC DeRosa, A Lin, P Mallikaratchy… - Nature Reviews …, 2023 - nature.com
The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …

DNA-based nanomaterials as drug delivery platforms for increasing the effect of drugs in tumors

AN Shishparenok, VV Furman, DD Zhdanov - Cancers, 2023 - mdpi.com
Simple Summary The use of drugs based on nucleic acids is a promising direction in
antitumor therapy. Some modified oligonucleotide analogs, such as antisense …

Recent progress in enhanced cancer diagnosis, prognosis, and monitoring using a combined analysis of the number of circulating tumor cells (CTCs) and other …

TNA Nguyen, PS Huang, PY Chu, CH Hsieh, MH Wu - Cancers, 2023 - mdpi.com
Simple Summary Counting the number of circulating tumor cells (CTCs) in blood samples
has been recognized as being clinically useful. However, challenges like the rarity and …

Advances on liquid biopsy analysis for glioma diagnosis

P Skouras, M Markouli, T Kalamatianos, G Stranjalis… - Biomedicines, 2023 - mdpi.com
Gliomas comprise the most frequent primary central nervous system (CNS) tumors,
characterized by remarkable genetic and epigenetic heterogeneity, difficulty in monitoring …

Visualization of Brain Tumors with Infrared-Labeled Aptamers for Fluorescence-Guided Surgery

G Zamay, A Koshmanova, A Narodov… - Journal of the …, 2024 - ACS Publications
Gliomas remain challenging brain tumors to treat due to their infiltrative nature. Accurately
identifying tumor boundaries during surgery is crucial for successful resection. This study …

Characterizing Aptamer Interaction with the Oncolytic Virus VV-GMCSF-Lact

MA Dymova, DO Malysheva, VK Popova… - Molecules, 2024 - mdpi.com
Aptamers are currently being investigated for their potential to improve virotherapy. They
offer several advantages, including the ability to prevent the aggregation of viral particles …

[HTML][HTML] Using Computer Modeling and Experimental Methods to Screen for Aptamers That Bind to the VV-GMCSF-LACT Virus

M Dymova, N Vasileva, D Malysheva, A Ageenko… - Molecules, 2024 - mdpi.com
Oncolytic virotherapy is a promising approach for cancer treatment. However, when
introduced into the body, the virus provokes the production of virus-neutralizing antibodies …

Nervous necrosis virus induced vacuolization is a Rab5-and actin-dependent process

J Liu, L Wang, X Zhang, S Wang, Q Qin - Virulence, 2024 - Taylor & Francis
Cytoplasmic vacuolization is commonly induced by bacteria and viruses, reflecting the
complex interactions between pathogens and the host. However, their characteristics and …

[HTML][HTML] Aptamer's Structure Optimization for Better Diagnosis and Treatment of Glial Tumors

AA Koshmanova, PV Artyushenko, IA Shchugoreva… - Cancers, 2024 - mdpi.com
Background: Oncological diseases are a major focus in medicine, with millions diagnosed
each year, leading researchers to seek new diagnostic and treatment methods. One …

Аптамеры для диагностики и лечения глиальных опухолей человека

ТН Замай, МА Дымова, АА Народов… - Сибирский …, 2023 - siboncoj.ru
Аптамеры для диагностики и лечения глиальных опухолей человека | Замай |
Сибирский онкологический журнал Сибирский онкологический журнал Sibirskij …