Male infertility and obesity

MA Rasouli, DA Dumesic, V Singhal - Current Opinion in …, 2024 - journals.lww.com
This review highlights how obesity impairs male reproduction through complex mechanisms,
including metabolic syndrome, lipotoxicity, sexual dysfunction, hormonal and adipokine …

Unraveling the impact of hyperleptinemia on female reproduction: insights from transgenic pig model

MA Jamal, Y Cheng, D Jiao, W Cheng, D Zou… - Biological Research, 2024 - Springer
Background Infertility is a growing global health concern affecting millions of couples
worldwide. Among several factors, an extreme body weight adversely affects reproductive …

Association between cardiometabolic index and testosterone levels in adult men: NHANES 2011–2016

X Huang, L Hu, S Tao, T Xue, J Li, X Wang - Plos one, 2024 - journals.plos.org
Objective Exploring the relationship between the cardiometabolic index (CMI) and serum
testosterone levels as well as testosterone deficiency in American adult males. Additionally …

[PDF][PDF] Aging, testosterone and male fertility therapy: a review

Y Pyo, KH Kwon - Journal of Men's Health, 2024 - oss.jomh.org
Men's fertility declines as they age. Reduced reproductive function lowers testosterone
levels, which leads to poor sperm quality and low fertility. This article summarizes the …

Type 1 diabetes impairs the activity of rat testicular somatic and germ cells through NRF2/NLRP3 pathway-mediated oxidative stress

M Venditti, MZ Romano, S Boccella… - Frontiers in …, 2024 - frontiersin.org
Background It is well known that metabolic disorders, including type 1 diabetes (T1D), are
often associated with reduced male fertility, mainly increasing oxidative stress and impairing …

[HTML][HTML] Apigenin improves testosterone synthesis by regulating endoplasmic reticulum stress

L Wu, J Qu, L Mou, C Liu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Obesity is a growing epidemic among reproductive-age men, which can cause and
exacerbate male infertility by means of associated comorbidities, endocrine abnormalities …

DNA Aptamer Raised against Advanced Glycation End Products Improves Sperm Concentration, Motility, and Viability by Suppressing Receptors for Advanced …

Y Mori, M Terasaki, N Osaka, T Fujikawa… - International Journal of …, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a risk factor for male infertility, but the underlying
molecular mechanisms remain unclear. Advanced glycation end products (AGEs) are …

Examining the causal relationship between sex hormone-binding globulin (SHBG) and infertility: A Mendelian randomization study

H Ma, Y Chen - Plos one, 2024 - journals.plos.org
Background The causal relationship between sex hormone-binding globulin (SHBG) and
infertility has remained unclear. Thus, we used Mendelian randomization (MR) to investigate …

Impact of Obesity on Pubertal Timing and Male Fertility

V Calcaterra, L Tiranini, VC Magenes, V Rossi… - Journal of Clinical …, 2025 - mdpi.com
Childhood obesity has profound effects on puberty in boys and girls, altering its timing,
progression, and associated hormonal changes. Also, later male fertility could be impaired …

Sindromul MOSH–o nouă viziune a hipogonadismului dobândit

V Ghenciu, I Arian, I Dumbrăveanu, M Creciun… - … Publică, Economie şi …, 2024 - ibn.idsi.md
Hipogonadismul masculin funcțional în asociere cu obezitatea a fost definit recent ca
hipogonadism secundar indus de obezitate–sindrom MOSH. Manifestările clinice sunt …