Senescence-associated inflammatory responses: aging and cancer perspectives

A Lasry, Y Ben-Neriah - Trends in immunology, 2015 - cell.com
Senescent cells, albeit not proliferating, are metabolically and transcriptionally active,
thereby capable of affecting their microenvironment, notably via the production of …

Programmed ageing: decline of stem cell renewal, immunosenescence, and Alzheimer's disease

R Lathe, D St. Clair - Biological Reviews, 2023 - Wiley Online Library
The characteristic maximum lifespan varies enormously across animal species from a few
hours to hundreds of years. This argues that maximum lifespan, and the ageing process that …

Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae

KM Beavers, EW Van Buren, AM Rossin… - Nature …, 2023 - nature.com
Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral
diseases on record, affects over 22 species of reef-building coral and is decimating reefs …

Looking down on NF-κB

LM Williams, TD Gilmore - Molecular and Cellular Biology, 2020 - Am Soc Microbiol
The diversified NF-κB transcription factor family has been extensively characterized in
organisms ranging from flies to humans. However, homologs of NF-κB and many upstream …

Chitosan degradation products facilitate peripheral nerve regeneration by improving macrophage-constructed microenvironments

Y Zhao, Y Wang, J Gong, L Yang, C Niu, X Ni, Y Wang… - Biomaterials, 2017 - Elsevier
Chitosan-based artificial nerve grafts have been widely employed to repair peripheral nerve
defects. Our previous study has shown that chitosan constructed nerve graft not only …

Twenty years of the 'Preparation for Oxidative Stress'(POS) theory: Ecophysiological advantages and molecular strategies

M Giraud-Billoud, GA Rivera-Ingraham… - … and Physiology Part A …, 2019 - Elsevier
Freezing, dehydration, salinity variations, hypoxia or anoxia are some of the environmental
constraints that many organisms must frequently endure. Organisms adapted to these …

Hematopoietic plasticity mapped in Drosophila and other insects

D Hultmark, I Andó - Elife, 2022 - elifesciences.org
Hemocytes, similar to vertebrate blood cells, play important roles in insect development and
immunity, but it is not well understood how they perform their tasks. New technology, in …

Novel technologies uncover novel 'anti'-microbial peptides in Hydra shaping the species-specific microbiome

A Klimovich, TCG Bosch - Philosophical Transactions of …, 2024 - royalsocietypublishing.org
The freshwater polyp Hydra uses an elaborate innate immune machinery to maintain its
specific microbiome. Major components of this toolkit are conserved Toll-like receptor (TLR) …

Integrative biology of injury in animals

CW Rennolds, AE Bely - Biological Reviews, 2023 - Wiley Online Library
Mechanical injury is a prevalent challenge in the lives of animals with myriad potential
consequences for organisms, including reduced fitness and death. Research on animal …

Reactive oxygen species in planarian regeneration: an upstream necessity for correct patterning and brain formation

N Pirotte, AS Stevens, S Fraguas… - Oxidative medicine …, 2015 - Wiley Online Library
Recent research highlighted the impact of ROS as upstream regulators of tissue
regeneration. We investigated their role and targeted processes during the regeneration of …