[HTML][HTML] A cardiovascular simulator tailored for training and clinical uses

L Fresiello, G Ferrari, A Di Molfetta, K Zieliński… - Journal of Biomedical …, 2015 - Elsevier
Objective In the present work a cardiovascular simulator designed both for clinical and
training use is presented. Method The core of the simulator is a lumped parameter model of …

Reproduction of continuous flow left ventricular assist device experimental data by means of a hybrid cardiovascular model with baroreflex control

L Fresiello, K Zieliński, S Jacobs, A Di Molfetta… - Artificial …, 2014 - Wiley Online Library
Long‐term mechanical circulatory assistance opened new problems in ventricular assist
device—patient interaction, especially in relation to autonomic controls. Modeling studies …

[HTML][HTML] Effect of timing of umbilical cord clamping and birth on fetal to neonatal transition: OpenModelica-based virtual simulator-based approach

EH Sepúlveda-Oviedo, LEB Clavijo… - Biocybernetics and …, 2024 - Elsevier
The transition from fetal to newborn condition involves complex physiological adaptations for
extrauterine life. A crucial event in this process is the clamping of the umbilical cord, which …

In-silico evaluation of left ventricular unloading under varying speed continuous flow left ventricular assist device support

S Bozkurt, S Bozkurt - Biocybernetics and Biomedical Engineering, 2017 - Elsevier
Continuous flow left ventricular assist device (cf-LVAD) operating speed modulation
techniques are proposed to achieve different purposes such as improving arterial pulsatility …

An innovative adaptive control strategy for sensorized left ventricular assist devices

A Verbeni, R Fontana, M Silvestri… - … Circuits and Systems, 2014 - ieeexplore.ieee.org
Nowadays advanced heart failure is mainly treated through heart transplantation. However,
the low availability of donors makes the research of alternative therapies urgent. Continuous …

Modeling and simulation of speed selection on left ventricular assist devices

AT Tzallas, NS Katertsidis, EC Karvounis… - Computers in biology …, 2014 - Elsevier
The control problem for LVADs is to set pump speed such that cardiac output and pressure
perfusion are within acceptable physiological ranges. However, current technology of …

Estimation of systemic vascular resistance using built-in sensing from an implanted left ventricular assist device

ES Rapp, SR Pawar, JR Gohean… - … and Science in …, 2019 - asmedigitalcollection.asme.org
This paper presents an approach for real-time estimation of the systemic vascular resistance
(SVR) of heart failure patients who have a left ventricular assist device (LVAD). Notably, an …

A decision support system for the treatment of patients with ventricular assist device support

EC Karvounis, MG Tsipouras, AT Tzallas… - … of Information in …, 2014 - thieme-connect.com
Background: Heart failure (HF) is affecting millions of people every year and it is
characterized by impaired ventricular performance, exercise intolerance and shortened life …

A Gaussian mixture model to detect suction events in rotary blood pumps

AT Tzallas, G Rigas, EC Karvounis… - 2012 IEEE 12th …, 2012 - ieeexplore.ieee.org
In this paper, we introduce a new suction detection approach based on online learning of a
Gaussian Mixture Model (GMM) with constrained parameters to model the reduction in pump …

[PDF][PDF] Circulatory modelling as a clinical decision support and an educational tool

G Ferrari, A Di Molfetta, K Zieliński, L Fresiello - Biomed. Data J, 2015 - biomed-data.eu
Circulatory models can be used in support of clinical decision making. Based on this
assumption, we developed a modelling platform composed of a family of circulatory models …