Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

The 2018–2019 period marks the centennial of the “Spanish” influenza pandemic, which
caused at least 50 million deaths worldwide. The unprecedented nature of the pandemic's …

The design of proteins that bind to a specific site on the surface of a target protein using no
information other than the three-dimensional structure of the target remains a challenge …

The broad-spectrum antiviral drug Arbidol shows efficacy against influenza viruses by
targeting the hemagglutinin (HA) fusion machinery. However, the structural basis of the …

Aquatic birds harbor diverse influenza A viruses and are a major viral reservoir in nature.
The recent discovery of influenza viruses of a new H17N10 subtype in Central American fruit …

Enveloped viruses enter cells by inducing fusion of viral and cellular membranes, a process
catalyzed by a specialized membrane-fusion protein expressed on their surface. This review …

The recent emergence of a novel avian A/H 7 N 9 influenza virus in poultry and humans in C
hina, as well as laboratory studies on adaptation and transmission of avian A/H 5 N 1 …

Structure determination of the HIV‐1 envelope glycoprotein (Env) presented a number of
challenges, but several high‐resolution structures have now become available. In 2013 …

Cervical cancer is the second most common cancer in women worldwide, and knowledge
regarding its cause and pathogenesis is expanding rapidly. Persistent infection with one of …

Influenza viruses cause annual epidemics and occasional pandemics that have claimed the
lives of millions. The emergence of new strains will continue to pose challenges to public …