Outer membrane vesicles: biogenesis, functions, and issues

R Juodeikis, SR Carding - Microbiology and Molecular Biology …, 2022 - Am Soc Microbiol
This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial
extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the …

Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria

JE Horne, DJ Brockwell, SE Radford - Journal of Biological Chemistry, 2020 - ASBMB
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …

Lipids mediate supramolecular outer membrane protein assembly in bacteria

MN Webby, AO Oluwole, C Pedebos, PG Inns… - Science …, 2022 - science.org
β Barrel outer membrane proteins (OMPs) cluster into supramolecular assemblies that give
function to the outer membrane (OM) of Gram-negative bacteria. How such assemblies form …

Peptidoglycan maturation controls outer membrane protein assembly

G Mamou, F Corona, R Cohen-Khait, NG Housden… - Nature, 2022 - nature.com
Linkages between the outer membrane of Gram-negative bacteria and the peptidoglycan
layer are crucial for the maintenance of cellular integrity and enable survival in challenging …

Phase separation in the outer membrane of Escherichia coli

G Benn, IV Mikheyeva, PG Inns… - Proceedings of the …, 2021 - National Acad Sciences
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with
phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer leaflet. The OM is …

The multifarious roles of Tol-Pal in Gram-negative bacteria

J Szczepaniak, C Press… - FEMS Microbiology …, 2020 - academic.oup.com
In the 1960s several groups reported the isolation and preliminary genetic mapping of
Escherichia coli strains tol erant towards the action of colicins. These pioneering studies kick …

The Tol-Pal system is required for peptidoglycan-cleaving enzymes to complete bacterial cell division

AA Yakhnina, TG Bernhardt - Proceedings of the National …, 2020 - National Acad Sciences
Tol-Pal is a multiprotein system present in the envelope of Gram-negative bacteria.
Inactivation of this widely conserved machinery compromises the outer membrane (OM) …

Tunable force transduction through the Escherichia coli cell envelope

DP Williams-Jones, MN Webby… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane (OM) of Gram-negative bacteria is not energised and so processes
requiring a driving force must connect to energy-transduction systems in the inner …

Localization, assembly, and activation of the Escherichia coli cell division machinery

PA Levin, A Janakiraman - EcoSal Plus, 2021 - Am Soc Microbiol
Decades of research, much of it in Escherichia coli, have yielded a wealth of insight into
bacterial cell division. Here, we provide an overview of the E. coli division machinery with an …

How bacteria establish and maintain outer membrane lipid asymmetry

WB Tan, SS Chng - Annual Review of Microbiology, 2024 - annualreviews.org
Gram-negative bacteria build an asymmetric outer membrane (OM), with
lipopolysaccharides (LPS) and phospholipids (PLs) occupying the outer and inner leaflets …