Exposure of blood to a foreign surface in the form of a diagnostic or therapeutic biomaterial
device or implanted cells or tissue elicits an immediate, evolutionarily conserved …

Clinical islet transplantation has the potential to cure type 1 diabetes. Despite recent
therapeutic success, it is still uncommon because transplanted islets are damaged by …

OBJECTIVE Reparixin is an inhibitor of CXCR1/2 chemokine receptor shown to be an
effective anti-inflammatory adjuvant in a pilot clinical trial in allotransplant recipients …

Type 1 diabetes mellitus (T1DM) is characterized by absolute insulin deficiency primarily
due to autoimmune destruction of pancreatic β‐cells. The prevailing treatment for T1DM …

Pancreatitis is pathologic inflammation of the pancreas characterized by acinar cell
destruction and oxidative stress. Repeated pancreatic insults can result in the development …

Successful pancreas or islet transplantation is currently the only cure for type 1 diabetes
mellitus. Since the first pancreas transplant in 1966, there have been various refinements of …

Since the late 20th century, advances in pancreatic islet transplantation have targeted
improved glycemic control and fewer hypoglycemic events in patients with type 1 diabetes …

A major portion of spinal cord injury (SCI) cases occur in the cervical region, where essential
components of the respiratory neural circuitry are located. Phrenic motor neurons (PhMNs) …

Introduction Amyotrophic lateral sclerosis (ALS) is an invariably lethal progressive disease,
causing degeneration of neurons and muscle. No current treatment halts or reverses …

Microbial polysaccharides (MPs) are biopolymers secreted by microorganisms such as
bacteria and fungi during their metabolic processes. Compared to polysaccharides derived …