Measurements inside the human body are complicated. Here, we provide a short
introduction of the main requirements for the successful in vivo determination of dopamine …

The tree shrew (Tupaia belangeri) has long been proposed as a suitable alternative to non-
human primates (NHPs) in biomedical and laboratory research due to its close evolutionary …

Medium spiny neurons (MSNs) in the striatum, which can be divided into D1 and D2 MSNs,
originate from the lateral ganglionic eminence (LGE). Previously, we reported that Six3 is a …

The globus pallidus (GP) of primates is divided conventionally into distinct internal and
external parts. The literature repeats since 1930 the opinion that the homolog of the primate …

Major depressive disorder (MDD) is associated with significant morbidity and mortality. Most
antidepressant medications target the serotonin and norepinephrine transporters, but a …

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective
therapy. Animal models effectively reproducing IPF disease features are needed to study the …

Background The basal ganglia are important structures for the release of dopamine in the
limbic circuits of the midbrain, and the striatum and globus pallidus are the major nuclei of …

The surge in demand for experimental monkeys has led to a rapid increase in their costs.
Consequently, there is a growing need for a cost-effective model of Parkinson disease (PD) …

It remains unknown whether the Chinese tree shrew, regarded as the closest sister of
primate, has evolved a dorsolateral prefrontal cortex (dlPFC) comparable with primates that …

The cerebellum is involved in the control of movement, emotional responses, and reward
processing. The tree shrew is the closest living relative of primates. However, little is known …