An overview of microRNAs: Biology, functions, therapeutics, and analysis methods

K Saliminejad, HR Khorram Khorshid… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in
posttranscriptional regulation of gene expression. They are powerful regulators of various …

Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

HMDD v3. 0: a database for experimentally supported human microRNA–disease associations

Z Huang, J Shi, Y Gao, C Cui, S Zhang, J Li… - Nucleic acids …, 2019 - academic.oup.com
Comprehensive databases of microRNA–disease associations are continuously demanded
in biomedical researches. The recently launched version 3.0 of Human MicroRNA Disease …

M2 macrophage-derived exosomes promote cell migration and invasion in colon cancer

J Lan, LI Sun, F Xu, L Liu, F Hu, D Song, Z Hou, W Wu… - Cancer research, 2019 - AACR
Clinical and experimental evidence has shown that tumor-associated macrophages promote
cancer initiation and progression. However, the macrophage-derived molecular …

Updated review of advances in microRNAs and complex diseases: taxonomy, trends and challenges of computational models

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
Since the problem proposed in late 2000s, microRNA–disease association (MDA)
predictions have been implemented based on the data fusion paradigm. Integrating diverse …

mirDIP 4.1—integrative database of human microRNA target predictions

T Tokar, C Pastrello, AEM Rossos… - Nucleic acids …, 2018 - academic.oup.com
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …

Fusobacterium nucleatum increases proliferation of colorectal cancer cells and tumor development in mice by activating toll-like receptor 4 signaling to nuclear factor …

Y Yang, W Weng, J Peng, L Hong, L Yang, Y Toiyama… - Gastroenterology, 2017 - Elsevier
Background & Aims Nearly 20% of the global cancer burden can be linked to infectious
agents. Fusobacterium nucleatum promotes tumor formation by epithelial cells via unclear …

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

CH Chou, NW Chang, S Shrestha, SD Hsu… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which
negatively regulate the gene expression at the post-transcriptional level. This study …

IGF2BP1 promotes SRF-dependent transcription in cancer in am6A- and miRNA-dependent manner

S Müller, M Glaß, AK Singh, J Haase… - Nucleic acids …, 2019 - academic.oup.com
The oncofetal mRNA-binding protein IGF2BP1 and the transcriptional regulator SRF
modulate gene expression in cancer. In cancer cells, we demonstrate that IGF2BP1 …

Base-resolution mapping reveals distinct m1A methylome in nuclear-and mitochondrial-encoded transcripts

X Li, X Xiong, M Zhang, K Wang, Y Chen, J Zhou… - Molecular cell, 2017 - cell.com
Gene expression can be post-transcriptionally regulated via dynamic and reversible RNA
modifications. N 1-methyladenosine (m 1 A) is a recently identified mRNA modification; …