[HTML][HTML] Challenges and recommendations when selecting empirical antibiotics in patients with cirrhosis

M Dirchwolf, GG Perdiguero, I Mc Grech… - World Journal of …, 2023 - ncbi.nlm.nih.gov
There is abundant evidence that bacterial infections are severe complications in patients
with cirrhosis, being the most frequent trigger of acute-on-chronic liver failure and causing …

British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis–part 2: decompensated cirrhosis

D Mansour, S Masson, L Corless, AC Douds… - Frontline …, 2023 - fg.bmj.com
There are two distinct phases in the natural history of cirrhosis: compensated disease
(corresponding to Child Pugh A and early Child Pugh B disease), where the patient may be …

Cotrimoxazole and targeted antibiotic prophylaxis for transrectal prostate biopsy: a single-center study

M Jahnen, T Amiel, F Kirchoff, JW Büchler… - World journal of …, 2024 - Springer
Purpose The recent restriction on the use of fluoroquinolones for prophylaxis by the
European Commission has left a gap in clear recommendations for practical antibiotic …

Reply: Antibiotic prophylaxis in palliative patients with cirrhosis: Stewardship or gatekeeping?

A O'Brien, D Crocombe - Hepatology Communications, 2023 - journals.lww.com
We read with interest Haddadin et al's letter and wholeheartedly support their innovation
and leadership in palliative interventional trials in advanced liver disease. We are grateful to …

[HTML][HTML] Comparison of Rifaximin Alone and With Quinolones in the Primary Prevention of Spontaneous Bacterial Peritonitis in Patients With Decompensated Chronic …

T Zaman, MBA Attari, A Ahmad, MA Butt, K Fayyaz… - Cureus, 2024 - ncbi.nlm.nih.gov
Background In cirrhotic patients with ascites, primary prevention of spontaneous bacterial
peritonitis (SBP) is a key strategy to lower morbidity and death. Rifaximin and …

Diagnosis and management of ascites and hepatorenal syndrome (acute kidney injury) in cirrhosis

D Crocombe, A O'Brien - Medicine, 2023 - Elsevier
Ascites is the most common decompensation-defining complication of cirrhosis and
represents a watershed moment, with median survival falling from> 12 years for …

[HTML][HTML] In search of a roadmap towards improving care of patients with cirrhosis and ascites, could a platform trial design transform clinical research?

A O'Brien - Hepatobiliary Surgery and Nutrition, 2022 - ncbi.nlm.nih.gov
© HepatoBiliary Surgery and Nutrition. All rights reserved. HepatoBiliary Surg Nutr 2022; 11
(6): 889-892| https://dx. doi. org/10.21037/hbsn-22-478 de-escalation or discontinuation of …

[HTML][HTML] Antimicrobial prophylaxis in decompensated cirrhosis: friend or foe?

D Crocombe, A O'Brien - Hepatology Communications, 2023 - journals.lww.com
BACKGROUND Infection is a major driver of mortality and morbidity in decompensated
cirrhosis, and the risk of both community-acquired and nosocomial infection correlates with …

[PDF][PDF] Refractory ascites in end stage liver disease focussing on the use of long term drains in a palliative setting

L Macken - 2023 - cris.brighton.ac.uk
Refractory ascites in end stage liver disease focussing on the use of long term drains in a
palliative setting Page 1 Refractory ascites in end stage liver disease focussing on the use of …