Enzymes involved in metabolism of extracellular nucleotides and nucleosides: functional implications and measurement of activities

GG Yegutkin - Critical reviews in biochemistry and molecular …, 2014 - Taylor & Francis
Extracellular nucleotides and nucleosides mediate diverse signaling effects in virtually all
organs and tissues. Most models of purinergic signaling depend on functional interactions …

The extended human PTP ome: A growing tyrosine phosphatase family

A Alonso, R Pulido - The FEBS journal, 2016 - Wiley Online Library
Tyr phosphatases are, by definition, enzymes that dephosphorylate phospho‐Tyr (pT yr)
from proteins. This activity is found in several structurally diverse protein families, including …

Tumor suppressive protein phosphatases in human cancer: Emerging targets for therapeutic intervention and tumor stratification

B Meeusen, V Janssens - The international journal of biochemistry & cell …, 2018 - Elsevier
Aberrant protein phosphorylation is one of the hallmarks of cancer cells, and in many cases
a prerequisite to sustain tumor development and progression. Like protein kinases, protein …

Altered glycosylation in prostate cancer

RR Drake, EE Jones, TW Powers… - Advances in cancer …, 2015 - Elsevier
Prostate cancer is annually the most common newly diagnosed cancer in men. The prostate
functions as a major secretory gland for the production of glycoproteins critical to sperm …

The proteomics of prostate cancer exosomes

RR Drake, T Kislinger - Expert review of proteomics, 2014 - Taylor & Francis
Exosomes and other microvesicles are emerging as rich reservoirs of tumor-specific proteins
and biomarkers for cancer detection and progression. For prostate cancer, exosomes …

Enamel defects in Acp4R110C/R110C mice and human ACP4 mutations

T Liang, SK Wang, C Smith, H Zhang, Y Hu… - Scientific Reports, 2022 - nature.com
Abstract Human ACP4 (OMIM* 606362) encodes a transmembrane protein that belongs to
histidine acid phosphatase (ACP) family. Recessive mutations in ACP4 cause non …

The sperm-associated antigen 6 interactome and its role in spermatogenesis

Y Liu, L Zhang, W Li, Q Huang, S Yuan, Y Li… - …, 2019 - rep.bioscientifica.com
Mammalian SPAG6, the orthologue of Chlamydomonas reinhardtii PF16, is a component of
the central apparatus of the “9+ 2” axoneme that controls ciliary/flagellar motility, including …

Lower brain-derived neurotrophic factor levels associated with worsening fatigue in prostate cancer patients during repeated stress from radiation therapy

LN Saligan, N Lukkahatai, G Holder… - The World Journal of …, 2016 - Taylor & Francis
Objectives. Fatigue during cancer treatment is associated with depression. Neurotrophic
factors play a major role in depression and stress and might provide insight into …

The extended family of protein tyrosine phosphatases

A Alonso, CE Nunes-Xavier, Y Bayón… - … : Methods and Protocols, 2016 - Springer
In higher eukaryotes, the Tyr phosphorylation status of cellular proteins results from the
coordinated action of Protein Tyrosine Kinases (PTKs) and Protein Tyrosine Phosphatases …

Characterization of HMGB1/2 interactome in prostate cancer by yeast two hybrid approach: potential pathobiological implications

A Barreiro-Alonso, M Cámara-Quílez… - Cancers, 2019 - mdpi.com
High mobility group box B (HMGB) proteins are pivotal in the development of cancer.
Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement …