A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics

J Anjum, S Mitra, R Das, R Alam, A Mojumder… - Pharmacological …, 2022 - Elsevier
Abnormalities in the mitogen-activated protein kinase (MAPK) signaling pathway are a key
contributor to the carcinogenesis process and have therefore been implicated in several …

The interaction between flavonoids and intestinal microbes: A review

HH Xiong, SY Lin, LL Chen, KH Ouyang, WJ Wang - Foods, 2023 - mdpi.com
In recent years, research on the interaction between flavonoids and intestinal microbes have
prompted a rash of food science, nutriology and biomedicine, complying with future research …

Immunopharmacological activities of luteolin in chronic diseases

L Huang, MY Kim, JY Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

Luteolin, a potent anticancer compound: from chemistry to cellular interactions and synergetic perspectives

H Singh Tuli, P Rath, A Chauhan, K Sak, D Aggarwal… - Cancers, 2022 - mdpi.com
Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

Luteolin, inflammation and cancer: Special emphasis on gut microbiota

L Franza, V Carusi, E Nucera, F Pandolfi - Biofactors, 2021 - Wiley Online Library
Luteolin belongs to the family of flavonoids, which have anti‐inflammatory functions,
potentially useful in a clinical context, particularly for patients suffering from cancer …

Multi-faceted role of luteolin in cancer metastasis: EMT, angiogenesis, ECM degradation and apoptosis

MT Rocchetti, F Bellanti, M Zadorozhna… - International Journal of …, 2023 - mdpi.com
Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone), a member of the flavonoid family derived from
plants and fruits, shows a wide range of biomedical applications. In fact, due to its anti …

The role of the aryl hydrocarbon receptor (AhR) and its ligands in breast cancer

S Safe, L Zhang - Cancers, 2022 - mdpi.com
Simple Summary The aryl hydrocarbon receptor (AhR) is expressed in breast cancer cells
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …

Influence of olive oil and its components on breast cancer: Molecular mechanisms

R Moral, E Escrich - Molecules, 2022 - mdpi.com
Breast cancer is the most frequent malignant neoplasia and a leading cause of mortality in
women worldwide. The Mediterranean diet has been proposed as a healthy dietary pattern …

Luteolin ameliorates experimental pulmonary arterial hypertension via suppressing hippo-YAP/PI3K/AKT signaling pathway

W Zuo, N Liu, Y Zeng, Z Xiao, K Wu, F Yang… - Frontiers in …, 2021 - frontiersin.org
Luteolin is a flavonoid compound with a variety of pharmacological effects. In this study, we
explored the effects of luteolin on monocrotaline (MCT) induced rat pulmonary arterial …

Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches

M Shi, Z Chen, H Gong, Z Peng, Q Sun… - Phytotherapy …, 2024 - Wiley Online Library
Current pharmaceutical research is energetically excavating the pharmacotherapeutic role
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …