Organ transplantation: historical perspective and current practice

CJE Watson, JH Dark - British journal of anaesthesia, 2012 - academic.oup.com
Over the course of the last century, organ transplantation has overcome major technical
limitations to become the success it is today. The breakthroughs include developing …

Challenges to liver transplantation and strategies to improve outcomes

P Dutkowski, M Linecker, ML DeOliveira, B Müllhaupt… - Gastroenterology, 2015 - Elsevier
Liver transplantation (LT) is a highly successful treatment for many patients with
nonmalignant and malignant liver diseases. However, there is a worldwide shortage of …

Development and validation of a comprehensive model to estimate early allograft failure among patients requiring early liver retransplant

AW Avolio, A Franco, A Schlegel, Q Lai, S Meli… - JAMA …, 2020 - jamanetwork.com
Importance Expansion of donor acceptance criteria for liver transplant increased the risk for
early allograft failure (EAF), and although EAF prediction is pivotal to optimize transplant …

[HTML][HTML] Liver transplantation using fatty livers: always feasible?

L McCormack, P Dutkowski, AM El-Badry… - Journal of hepatology, 2011 - Elsevier
Steatotic liver grafts represent the most common type of “extended criteria” organs that have
been introduced during the last two decades due to the disparity between liver transplant …

Donor hepatic steatosis and outcome after liver transplantation: a systematic review

MJJ Chu, AJ Dare, ARJ Phillips… - Journal of Gastrointestinal …, 2015 - Elsevier
Background There is increasing need to expand availability of donor liver grafts, including
steatotic livers. Steatotic liver is associated with poor outcome post-transplantation but with …

Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease: A decalogue from the Italian Association for the Study of the Liver (AISF) …

P Loria, LE Adinolfi, S Bellentani, E Bugianesi… - Digestive and Liver …, 2010 - Elsevier
We report the evidence-based Italian Association for the Study of Liver guidelines for the
appropriate diagnosis and management of patients with nonalcoholic fatty liver disease in …

New insights in mechanisms and therapeutics for short-and long-term impacts of hepatic ischemia reperfusion injury post liver transplantation

H Liu, K Man - International journal of molecular sciences, 2021 - mdpi.com
Liver transplantation has been identified as the most effective treatment for patients with end-
stage liver diseases. However, hepatic ischemia reperfusion injury (IRI) is associated with …

The use of fatty liver grafts in modern allocation systems: risk assessment by the balance of risk (BAR) score

P Dutkowski, A Schlegel, K Slankamenac… - Annals of …, 2012 - journals.lww.com
Objective: To integrate the amount of hepatic steatosis in modern liver allocation models.
Background: The aim of this study was to combine the 2 largest liver transplant databases …

Use of severely steatotic grafts in liver transplantation: a matched case-control study

L McCormack, H Petrowsky, W Jochum… - Annals of …, 2007 - journals.lww.com
Background: Although there is a worldwide need to expand the pool of available liver grafts,
cadaveric livers with severe steatosis (> 60%) are discarded for orthotopic liver …

Omega 3–Omega 6: What is right for the liver?

AM El-Badry, R Graf, PA Clavien - Journal of hepatology, 2007 - Elsevier
Linoleic and α-linolenic acids are the fatty acids designated as “essential” since they are not
synthesized by mammalian cells and must be provided in the diet. The recent dietary shift …