Cryptococcal meningitis is a common opportunistic infection in AIDS patients, particularly in
Southeast Asia and Africa. Cases also occur in patients with other forms of …

The persistence of high morbidity and mortality from systemic fungal infections despite the
availability of novel antifungals points to the need for effective treatment strategies …

With increasing numbers of immune-compromised patients with malignancy, hematologic
disease, and HIV, as well as those receiving immunosupressive drug regimens for the …

Fungal infection has become one of the leading causes of hospital-acquired infections with
high mortality rates. Furthermore, drug resistance is common for fungus-causing diseases …

Background It frequently takes more than 2 weeks for drug treatments for cryptococcal
meningitis to sterilise cerebrospinal fluid (CSF). In-vitro and animal studies lend support to …

The emerging and sustained resistance to antibiotics and the poor pipeline of new
antibacterials is creating a major health issue worldwide. Bacterial pathogens are …

Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

Abstract (See the Editorial Commentary by Bennett, on pages 129–30.) Background. HIV-
associated cryptococcal meningitis is associated with an estimated 600 000 deaths …

The combination of drugs is a common practice for enhancing the efficiency of drug
treatment, but selection of the optimal combination and the optimal doses remains a matter …

Neurological complications are frequent in renal transplant recipients and may largely
contribute to morbidity and mortality. The postransplant neurological complications may be …