Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

Microbial biomanufacturing, powered by the advances of synthetic biology, has attracted
growing interest for the production of diverse products. In contrast to conventional microbes …

Metabolic efficiency profoundly influences organismal fitness. Nonphotosynthetic organisms,
from yeast to mammals, derive usable energy primarily through glycolysis and respiration …

Succinic acid (SA) is an important C4-dicarboxylic acid. Microbial production of SA at low pH
results in low purification costs and hence good overall process economics. However, redox …

We investigated genomic diversity of a yeast species that is both an opportunistic pathogen
and an important industrial yeast. Under the name Candida krusei, it is responsible for about …

Saccharomyces cerevisiae is a workhorse of industrial biotechnology owing to the
organism's prominence in alcohol fermentation and the suite of sophisticated genetic tools …

Microbial chemical production is a rapidly growing industry, with much of the growth fueled
by advances in synthetic biology. New approaches have enabled rapid strain engineering …

Highlights•The use of inexpensive carbon sources is urgently needed for citric acid
production.•Low-pH process benefits lactic acid production.•Different strains and processes …

Traditional plastic products have caused serious environmental pollution due to difficulty to
be degraded in the natural environment. In the recent years, biodegradable plastics are …

Organisms exhibit extensive variation in ecological niche breadth, from very narrow
(specialists) to very broad (generalists). Two general paradigms have been proposed to …